The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …

The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Micro-nano biorobots based on bacteria have demonstrated great potential for tumor
diagnosis and treatment. The bacterial gene expression and drug release should be …

Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Therapeutic mRNA vaccination is an attractive approach to trigger antitumor immunity.
However, the mRNA delivery technology for customized tumor vaccine is still limited. In this …

The complex gastrointestinal environment and the intestinal epithelial barrier constrain the
design and effectiveness of orally administered tumour vaccines. Here we show that outer …

Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …

Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

Anti-cancer drugs with various mechanisms emerge in succession, but most of free
therapeutics are accompanied by some disadvantages, such as poor safety and …

Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …