Adipose–Muscle crosstalk in age-related metabolic disorders: The emerging roles of adipo-myokines
P Fang, Y She, M Yu, W Min, W Shang… - Ageing Research Reviews, 2023 - Elsevier
Obesity and type 2 diabetes account for a considerable proportion of the global burden of
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …
[HTML][HTML] Recent advances in the treatment of insulin resistance targeting molecular and metabolic pathways: fighting a losing battle?
M Wolosowicz, S Prokopiuk, TW Kaminski - Medicina, 2022 - mdpi.com
Diabetes Mellitus (DM) is amongst the most notable causes of years of life lost worldwide
and its prevalence increases perpetually. The disease is characterized as multisystemic …
and its prevalence increases perpetually. The disease is characterized as multisystemic …
Effect of exercise training on spexin level, appetite, lipid accumulation product, visceral adiposity index, and body composition in adults with type 2 diabetes
A Mohammadi, N Bijeh, M Moazzami… - … research for nursing, 2022 - journals.sagepub.com
Objective To compare the effects of resistance and aerobic training (RT and AT) on spexin
(SPX), appetite, lipid accumulation product (LAP), visceral adiposity index (VAI), and body …
(SPX), appetite, lipid accumulation product (LAP), visceral adiposity index (VAI), and body …
Novel insights on the role of spexin as a biomarker of obesity and related cardiometabolic disease
S Kumar, RT Mankowski, SD Anton… - International Journal of …, 2021 - nature.com
Abstract Spexin (SPX) is a 14-amino acid neuropeptide, discovered recently using
bioinformatic techniques. It is encoded by the Ch12: orf39 gene that is widely expressed in …
bioinformatic techniques. It is encoded by the Ch12: orf39 gene that is widely expressed in …
Spexin: Its role, regulation, and therapeutic potential in the hypothalamus
Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …
Adipose tissue spexin in physical exercise and age-associated diseases
P Fang, R Ge, Y She, J Zhao, J Yan, X Yu, Y Jin… - Ageing Research …, 2022 - Elsevier
It is known that a strong association exists between a suboptimal lifestyle (physical inactivity
and sedentary behavior and/or high calorie diet) and increased propensity of developing …
and sedentary behavior and/or high calorie diet) and increased propensity of developing …
Emerging central and peripheral actions of spexin in feeding behavior, leptin resistance and obesity
M Yu, M Ju, P Fang, Z Zhang - Biochemical Pharmacology, 2022 - Elsevier
Consumption of a high calorie diet with irregular eating and sedentary behavior habits is
typical of the current suboptimal lifestyle, contributing to the development of metabolic …
typical of the current suboptimal lifestyle, contributing to the development of metabolic …
Spexin may induce mitochondrial biogenesis in white and brown adipocytes via the hypothalamus-pituitary-thyroid (HPT) axis
Aim The present study aimed to investigate the effect of the intracerebroventricular (icv)
administration of spexin on the hypothalamus-pituitary-thyroid (HPT) axis (TRH, TSH, T4 and …
administration of spexin on the hypothalamus-pituitary-thyroid (HPT) axis (TRH, TSH, T4 and …
Spexin ameliorates skeletal muscle insulin resistance through activation of GAL2 receptor
M Yu, M Wang, S Han, L Han, Y Kan, J Zhao… - European Journal of …, 2022 - Elsevier
Skeletal muscle is a principal tissue involved in energy expenditure and glucose
metabolism. Although the results of our and other studies show that spexin could decrease …
metabolism. Although the results of our and other studies show that spexin could decrease …
[HTML][HTML] Spexin and galanin in metabolic functions and social behaviors with a focus on non-mammalian vertebrates
Spexin (SPX) and galanin (GAL) are two neuropeptides that are phylogenetically related
and have descended from a common ancestral gene. Considerable attention has been …
and have descended from a common ancestral gene. Considerable attention has been …