The human disease methylation database (DiseaseMeth, http://bioinfo. hrbmu. edu.
cn/diseasemeth/) is an interactive database that aims to present the most complete …

The mammalian genome is packaged into chromatin that is further compacted into three‐
dimensional structures consisting of distinct functional domains. The higher order structure …

Abstract Epigenome-Wide Association Study (EWAS) has become increasingly significant in
identifying the associations between epigenetic variations and different biological traits. In …

Abstract We present MethHC (http://MethHC. mbc. nctu. edu. tw), a database comprising a
systematic integration of a large collection of DNA methylation data and mRNA/microRNA …

Tumor suppressor genes (TSGs) are guardian genes that play important roles in controlling
cell proliferation processes such as cell-cycle checkpoints and inducing apoptosis …

The pathogenic mechanisms of prostate cancer (PCa) remain to be defined. In this study, we
utilized the Robust Rank Aggregation (RRA) method to integrate 10 eligible PCa microarray …

Short-read sequencing enables assessment of genetic and biochemical traits of individual
genomic regions, such as the location of genetic variation, protein binding and chemical …

The completion of the Human Genome Project lays a foundation for systematically studying
the human genome from evolutionary history to precision medicine against diseases. With …

DNA methylation is a prevalent epigenetic modification involved in regulating a number of
essential cellular processes, including genomic accessibility and transcriptional outcomes …

In the recent decade, high-throughput genotyping and next-generation sequencing
platforms have enabled genome-wide association studies (GWAS) of many complex human …