The role of neoadjuvant therapy in pancreatic cancer: a review

S Russo, J Ammori, J Eads, J Dorth - Future oncology, 2016 - Taylor & Francis
Controversy remains regarding neoadjuvant approaches in the treatment of pancreatic
cancer. Neoadjuvant therapy has several potential advantages over adjuvant therapy …

A single-arm, nonrandomized phase II trial of neoadjuvant gemcitabine and oxaliplatin in patients with resectable pancreas adenocarcinoma

EM O'Reilly, A Perelshteyn, WR Jarnagin… - Annals of …, 2014 - journals.lww.com
Background: The role for neoadjuvant systemic therapy in resectable pancreas
adenocarcinoma remains undefined. Objective: We evaluated the efficacy of gemcitabine …

Prospective phase II trial of neoadjuvant chemotherapy with gemcitabine and cisplatin for resectable adenocarcinoma of the pancreatic head

S Heinrich, BC Pestalozzi, M Schäfer… - Journal of Clinical …, 2008 - ascopubs.org
Purpose To test the safety of neoadjuvant chemotherapy for resectable pancreatic cancer.
Patients and Methods Patients with cytologically proven resectable adenocarcinoma of the …

Neoadjuvant chemotherapy generates a significant tumor response in resectable pancreatic cancer without increasing morbidity: results of a prospective phase II trial

S Heinrich, M Schäfer, A Weber, TF Hany… - Annals of …, 2008 - journals.lww.com
Objective: To evaluate the morbidity of pancreaticoduodenectomy after neoadjuvant
chemotherapy for resectable pancreatic cancer and to assess its histologic and metabolic …

[HTML][HTML] Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic …

M Tachezy, F Gebauer, C Petersen, D Arnold, M Trepel… - BMC cancer, 2014 - Springer
Background Median OS after surgery in curative intent for non-metastasized pancreas
cancer ranges under study conditions from 17.9 months to 23.6 months. Tumor recurrence …

[HTML][HTML] Neoadjuvant strategies for pancreatic cancer

F Polistina, G Di Natale, G Bonciarelli… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is the fourth cause of cancer death in Western countries, the only
chance for long term survival is an R0 surgical resection that is feasible in about 10%-20 …

[HTML][HTML] Survival impact of neoadjuvant therapy in resected pancreatic cancer: a prospective cohort study involving 18,332 patients from the National Cancer Data …

KA Mirkin, CS Hollenbeak, J Wong - International journal of surgery, 2016 - Elsevier
Background Pancreatic cancer carries a dismal prognosis, with surgical resection and
adjuvant therapy offering the only hope for long-term survival. Recently, neoadjuvant …

Surgical results after preoperative chemoradiation therapy for patients with pancreatic cancer

S Satoi, H Yanagimoto, H Toyokawa, K Takahashi… - Pancreas, 2009 - journals.lww.com
Objectives: The results of surgical therapy alone for pancreatic cancer are disappointing. We
explored surgical results after neoadjuvant chemoradiation therapy (NACRT) for patients …

Neoadjuvant chemoradiation in patients with potentially resectable pancreatic cancer

S Takai, S Satoi, H Yanagimoto, H Toyokawa… - Pancreas, 2008 - journals.lww.com
Objectives: To retrospectively evaluate the efficacy and tolerability of 5-fluorouracil and low-
dose cisplatin (FP)-based preoperative concurrent chemoradiotherapy (PCRT) and …

[HTML][HTML] Impact of preoperative chemoradiotherapy on survival in patients with resectable pancreatic cancer

P Vento, H Mustonen, T Joensuu… - World Journal of …, 2007 - ncbi.nlm.nih.gov
AIM: To explore whether preoperative chemoradiation therapy improves survival of patients
with pancreatic cancer undergoing resectional surgery. METHODS: Forty-seven patients …