Purpose Micron-scale computed tomography (micro-CT) imaging is a ubiquitous, cost-
effective, and non-invasive three-dimensional imaging modality. We review recent …

Organismal phenotypes frequently involve multiple organ systems. Histology is a powerful
way to detect cellular and tissue phenotypes, but is largely descriptive and subjective. To …

Vascular calcification describes the formation of mineralized tissue within the blood vessel
wall, and it is highly associated with increased cardiovascular morbidity and mortality in …

Ideal three-dimensional imaging of complex samples made up of micron-scale structures
extending over mm to cm, such as biological tissues, requires both wide field of view and …

We previously described X-ray histotomography, a high-resolution, non-destructive form of X-
ray microtomography (micro-CT) imaging customized for three-dimensional (3D), digital …

Investigations on the internal anatomy of stalked jellyfishes (Staurozoa) are crucial for
species descriptions and systematic studies on this taxon. Contrast-enhanced X-ray micro …

Recent studies have shown that micro-computed tomography (µCT) must be considered one
of the most suitable techniques for the non-invasive, three-dimensional (3D) visualization of …

Histological studies providing cellular insights into tissue architecture have been central to
biological discovery and remain clinically invaluable today. Extending histology to three …

Micro-CT imaging is a powerful tool for generating high resolution, isotropic three-
dimensional datasets of whole, centimeter-scale model organisms that can be used for …

Histological analysis of fluorescently labeled tissues has been a critical tool to understand
molecular organization in situ. However, assessing molecular structures within large cells …