Computational neuroethology: a call to action

SR Datta, DJ Anderson, K Branson, P Perona, A Leifer - Neuron, 2019 - cell.com
The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …

Measuring behavior across scales

GJ Berman - BMC biology, 2018 - Springer
The need for high-throughput, precise, and meaningful methods for measuring behavior has
been amplified by our recent successes in measuring and manipulating neural circuitry. The …

FlyWire: online community for whole-brain connectomics

S Dorkenwald, CE McKellar, T Macrina, N Kemnitz… - Nature …, 2022 - nature.com
Due to advances in automated image acquisition and analysis, whole-brain connectomes
with 100,000 or more neurons are on the horizon. Proofreading of whole-brain automated …

Unsupervised identification of the internal states that shape natural behavior

AJ Calhoun, JW Pillow, M Murthy - Nature neuroscience, 2019 - nature.com
Internal states shape stimulus responses and decision-making, but we lack methods to
identify them. To address this gap, we developed an unsupervised method to identify …

Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body

MJ Dolan, S Frechter, AS Bates, C Dan, P Huoviala… - Elife, 2019 - elifesciences.org
Animals exhibit innate behaviours to a variety of sensory stimuli including olfactory cues. In
Drosophila, one higher olfactory centre, the lateral horn (LH), is implicated in innate …

Sexual circuitry in Drosophila

TO Auer, R Benton - Current opinion in neurobiology, 2016 - Elsevier
Highlights•Sex-specific isoforms of Fruitless and Doublesex define dimorphic
circuitry.•Sensory pathways for chemical and auditory stimuli traced to the central …

The natverse, a versatile toolbox for combining and analysing neuroanatomical data

AS Bates, JD Manton, SR Jagannathan, M Costa… - Elife, 2020 - elifesciences.org
To analyse neuron data at scale, neuroscientists expend substantial effort reading
documentation, installing dependencies and moving between analysis and visualisation …

[HTML][HTML] Promises and challenges of human computational ethology

D Mobbs, T Wise, N Suthana, N Guzmán… - Neuron, 2021 - cell.com
The movements an organism makes provide insights into its internal states and motives.
This principle is the foundation of the new field of computational ethology, which links rich …

The neural basis for a persistent internal state in Drosophila females

D Deutsch, D Pacheco, L Encarnacion-Rivera… - Elife, 2020 - elifesciences.org
Sustained changes in mood or action require persistent changes in neural activity, but it has
been difficult to identify the neural circuit mechanisms that underlie persistent activity and …

Nested neural circuits generate distinct acoustic signals during Drosophila courtship

JL Lillvis, K Wang, HM Shiozaki, M Xu, DL Stern… - Current Biology, 2024 - cell.com
Many motor control systems generate multiple movements using a common set of muscles.
How are premotor circuits able to flexibly generate diverse movement patterns? Here, we …