Model validation and selection in metabolic flux analysis and flux balance analysis
JAM Kaste, Y Shachar‐Hill - Biotechnology Progress, 2024 - Wiley Online Library
Abstract 13C‐Metabolic Flux Analysis (13C‐MFA) and Flux Balance Analysis (FBA) are
widely used to investigate the operation of biochemical networks in both biological and …
widely used to investigate the operation of biochemical networks in both biological and …
Exploring Bacillus subtilis: Ecology, biotechnological applications, and future prospects
AA Akinsemolu, H Onyeaka, S Odion… - Journal of Basic …, 2024 - Wiley Online Library
From its early identification by Christian Gottfried Ehrenberg to its current prominence in
scientific research, Bacillus subtilis (B. subtilis) has emerged as a foundational model …
scientific research, Bacillus subtilis (B. subtilis) has emerged as a foundational model …
pan-Draft: automated reconstruction of species-representative metabolic models from multiple genomes
The accurate reconstruction of genome-scale metabolic models (GEMs) for unculturable
species poses challenges due to the incomplete and fragmented genetic information typical …
species poses challenges due to the incomplete and fragmented genetic information typical …
Bactabolize is a tool for high-throughput generation of bacterial strain-specific metabolic models
Metabolic capacity can vary substantially within a bacterial species, leading to ecological
niche separation, as well as differences in virulence and antimicrobial susceptibility …
niche separation, as well as differences in virulence and antimicrobial susceptibility …
Targeting the Bottlenecks in Levan Biosynthesis Pathway in Bacillus subtilis and Strain Optimization by Computational Modeling and Omics Integration
A Immanuel, RM Yennamalli… - OMICS: A Journal of …, 2024 - liebertpub.com
Levan is a fructan polymer with many industrial applications such as the formulation of
hydrogels, drug delivery, and wound healing, among others. To this end, metabolic systems …
hydrogels, drug delivery, and wound healing, among others. To this end, metabolic systems …
A validated pangenome-scale metabolic model for the Klebsiella pneumoniae species complex
The Klebsiella pneumoniae species complex (KpSC) is a major source of nosocomial
infections globally with high rates of resistance to antimicrobials. Consequently, there is …
infections globally with high rates of resistance to antimicrobials. Consequently, there is …
A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism that supports persistent co-existence of diverse lineages
The Klebsiella pneumoniae species complex inhabits a wide variety of hosts and
environments. Genomics has revealed the population comprises multiple …
environments. Genomics has revealed the population comprises multiple …
Molecular Advances in Microbial Metabolism 2.0
RM Martínez-Espinosa - International Journal of Molecular Sciences, 2024 - mdpi.com
The advances in molecular biology techniques and omics approaches have made it
possible to take giant steps in applied research in life sciences. In this context, microbiology …
possible to take giant steps in applied research in life sciences. In this context, microbiology …
Analysis of Bacillus subtilis Biomass Composition to Determine the Effects of Condition-Specific Biomass Objective Functions in iBsu1147
S Tande-Petersen - 2023 - ntnuopen.ntnu.no
Genome-scale metabolic models (GEMs) are mathematical models of an organisms cellular
metabolism under the assumption of steady-state. They are used for computation of …
metabolism under the assumption of steady-state. They are used for computation of …