Nanotechnology-based strategies for treatment of obesity, cancer and anti-microbial resistance: highlights of the department of science and innovation/mintek …

NRS Sibuyi, KL Moabelo, S Meyer, A Skepu… - Applied Sciences, 2022 - mdpi.com
Nanotechnology has recently received much interest in various fields, including medicine.
South Africa (SA) was the first country in Africa to adopt the technology with the aim of …

A review of the nucleic acid-based lateral flow assay for detection of breast cancer from circulating biomarkers at a point-of-care in low income countries

B Dyan, PP Seele, A Skepu, PS Mdluli, S Mosebi… - Diagnostics, 2022 - mdpi.com
The current levels of breast cancer in African women have contributed to the high mortality
rates among them. In South Africa, the incidence of breast cancer is also on the rise due to …

Proteinase K pretreatment for the quantitative recovery and sensitive detection of the tuberculosis biomarker mannose-capped lipoarabinomannan spiked into human …

E Clarke, R Robinson, LB Laurentius… - Analytical …, 2023 - ACS Publications
This paper reports on an investigation of an enzymatic pretreatment protocol using
proteinase K (ProK) for the analysis of human serum samples spiked with mannose-capped …

Development of gold-nanoparticle-based lateral flow immunoassays for rapid detection of TB ESAT-6 and CFP-10

PP Seele, B Dyan, A Skepu, C Maserumule… - Biosensors, 2023 - mdpi.com
The current study reports on the development of a rapid and cost-effective TB-antigen
diagnostic test for the detection of Mycobacterium biomarkers from non-sputum-based …

Evaluation of host protein biomarkers by ELISA from whole lysed peripheral blood for development of diagnostic tests for active tuberculosis

HN Garlant, K Ellappan, M Hewitt, P Perumal… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) remains a significant global health crisis and the number one cause of
death for an infectious disease. The health consequences in high-burden countries are …

Tuberculosis detection using a low-loss and highly sensitive photonic crystal fiber technique in the terahertz regime

SA Taya, DN Alhamss, AHM Almawgani, A Alzahrani… - JOSA B, 2023 - opg.optica.org
This research paper introduces a design and numerical investigation of a photonic crystal
fiber (PCF) sensor with a hollow core. The sensor is specifically designed to detect …

COVID-19 and Tuberculosis: Mathematical Modeling of Infection Spread Taking into Account Reduced Screening

A Starshinova, N Osipov, I Dovgalyk, A Kulpina… - Diagnostics, 2024 - mdpi.com
The COVID-19 pandemic resulted in the cessation of many tuberculosis (TB) support
programs and reduced screening coverage for TB worldwide. We propose a model that …

The application of aptamer in tuberculosis diagnosis: a systematic review

E Isaei, MH Sobhanipoor, M Rahimlou… - Tropical Diseases, Travel …, 2024 - Springer
Tuberculosis represents a significant menace to health, leading to millions of cases and
fatalities each year. Traditional diagnostic methods, while effective, have limitations …

Development and assessment of a novel magnetic nanoparticle antibody-conjugate and aptamer-based assay (MNp-Ab-Ap assay) for the rapid diagnosis of pleural …

P Sharma, RK Gupta, S Aittan, D Anthwal, M Dass… - Nanotheranostics, 2025 - ntno.org
Background: Pleural tuberculosis (pTB) is a diagnostic challenge because of its non-specific
clinical features, lack of accurate diagnostic tools and paucibacillary nature of the disease …

Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

CA Akinnawo, A Dube - Advanced Therapeutics, 2024 - Wiley Online Library
Globally a significant burden of tuberculosis (TB) is faced, which is difficult to eradicate due
to patients' non‐adherence, and drug‐resistant strains that are spreading at an alarming …