[HTML][HTML] Transmissibility and transmission of respiratory viruses

NHL Leung - Nature Reviews Microbiology, 2021 - nature.com
Human respiratory virus infections lead to a spectrum of respiratory symptoms and disease
severity, contributing to substantial morbidity, mortality and economic losses worldwide, as …

[HTML][HTML] Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling …

D Adeloye, P Song, Y Zhu, H Campbell… - The Lancet …, 2022 - thelancet.com
Background Chronic obstructive pulmonary disease (COPD) is an increasingly important
cause of morbidity, disability, and mortality worldwide. We aimed to estimate global …

[HTML][HTML] Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

VL Feigin, BA Stark, CO Johnson, GA Roth… - The Lancet …, 2021 - thelancet.com
Background Regularly updated data on stroke and its pathological types, including data on
their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are …

[HTML][HTML] The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial

AA Voors, CE Angermann, JR Teerlink, SP Collins… - Nature medicine, 2022 - nature.com
The sodium–glucose cotransporter 2 inhibitor empagliflozin reduces the risk of
cardiovascular death or heart failure hospitalization in patients with chronic heart failure, but …

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia… - Nature, 2021 - nature.com
Gene-editing technologies, which include the CRISPR–Cas nucleases–and CRISPR base
editors,, have the potential to permanently modify disease-causing genes in patients. The …

The 2020 report of the Lancet Countdown on health and climate change: responding to converging crises

N Watts, M Amann, N Arnell, S Ayeb-Karlsson… - The Lancet, 2021 - thelancet.com
The 2020 report of The Lancet Countdown on health and climate change: responding to
converging crises - The Lancet Skip to Main Content Advertisement The Lancet Journal This …

[HTML][HTML] Nanotechnology approaches for global infectious diseases

AR Kirtane, M Verma, P Karandikar, J Furin… - Nature …, 2021 - nature.com
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …

[HTML][HTML] Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025

X Lin, Y Xu, X Pan, J Xu, Y Ding, X Sun, X Song… - Scientific reports, 2020 - nature.com
Diabetes mellitus is a leading cause of mortality and reduced life expectancy. We aim to
estimate the burden of diabetes by type, year, regions, and socioeconomic status in 195 …

Sex and gender: modifiers of health, disease, and medicine

F Mauvais-Jarvis, NB Merz, PJ Barnes, RD Brinton… - The Lancet, 2020 - thelancet.com
Clinicians can encounter sex and gender disparities in diagnostic and therapeutic
responses. These disparities are noted in epidemiology, pathophysiology, clinical …

[HTML][HTML] Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017

M Amini, F Zayeri, M Salehi - BMC Public Health, 2021 - bmcpublichealth.biomedcentral.com
Cardiovascular diseases (CVDs) are one of the global leading causes of concern due to the
rising prevalence and consequence of mortality and disability with a heavy economic …