A current perspective on snake venom composition and constituent protein families

T Tasoulis, GK Isbister - Archives of toxicology, 2023 - Springer
Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …

The rise of genomics in snake venom research: recent advances and future perspectives

W Rao, K Kalogeropoulos, ME Allentoft… - …, 2022 - academic.oup.com
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …

Micro and macroevolution of sea anemone venom phenotype

EG Smith, JM Surm, J Macrander, A Simhi… - Nature …, 2023 - nature.com
Venom is a complex trait with substantial inter-and intraspecific variability resulting from
strong selective pressures acting on the expression of many toxic proteins. However …

The roles of balancing selection and recombination in the evolution of rattlesnake venom

DR Schield, BW Perry, RH Adams, ML Holding… - Nature ecology & …, 2022 - nature.com
The origin of snake venom involved duplication and recruitment of non-venom genes into
venom systems. Several studies have predicted that directional positive selection has …

Investigating toxin diversity and abundance in snake venom proteomes

T Tasoulis, TL Pukala, GK Isbister - Frontiers in Pharmacology, 2022 - frontiersin.org
Understanding snake venom proteomes is becoming increasingly important to understand
snake venom biology, evolution and especially clinical effects of venoms and approaches to …

One Size Fits All—Venomics of the Iberian Adder (Vipera seoanei, Lataste 1878) Reveals Low Levels of Venom Variation across Its Distributional Range

I Avella, M Damm, I Freitas, W Wüster, N Lucchini… - Toxins, 2023 - mdpi.com
European vipers (genus Vipera) are medically important snakes displaying considerable
venom variation, occurring at different levels in this group. The presence of intraspecific …

Venom gene sequence diversity and expression jointly shape diet adaptation in pitvipers

AJ Mason, ML Holding, RM Rautsaw… - Molecular Biology …, 2022 - academic.oup.com
Understanding the joint roles of protein sequence variation and differential expression
during adaptive evolution is a fundamental, yet largely unrealized goal of evolutionary …

A meta-analysis of the protein components in rattlesnake venom

A Deshwal, P Phan, J Datta, R Kannan… - Toxins, 2021 - mdpi.com
The specificity and potency of venom components give them a unique advantage in
developing various pharmaceutical drugs. Though venom is a cocktail of proteins, rarely are …

Intraspecific venom variation in the Iberian asp viper (Vipera aspis zinnikeri) across natural and intensive agricultural habitats

J Buldain, R Vitorino, T Lima, I Avella, Ó Zuazo… - Journal of …, 2025 - Elsevier
Snake venom composition varies at different levels. To date, comparative venom studies
have seldom taken into account the role of habitat type in the occurrence of snake venom …

Evolutionary allometry and ecological correlates of fang length evolution in vipers

ML Holding, VC Trevine, O Zinenko… - … of the Royal …, 2022 - royalsocietypublishing.org
Traits for prey acquisition form the phenotypic interface of predator–prey interactions. In
venomous predators, morphological variation in venom delivery apparatus like fangs and …