Oral vaccines are less immunogenic when given to infants in low-income compared with
high-income countries, limiting their potential public health impact. Here, we review factors …

In the decade since oral rotavirus vaccines (ORV) were recommended by the World Health
Organization for universal inclusion in all national immunization programs, significant yet …

Background Oral vaccines underperform in low-income and middle-income countries
compared with in high-income countries. Whether interventions can improve oral vaccine …

There is currently limited evidence regarding how the rotavirus vaccine dosing schedule
might be adjusted to improve vaccine performance. We quantified the impact of the …

ABSTRACT Introduction As of January 2021, rotavirus vaccination programs have been
implemented in 109 countries and their use has resulted in a positive impact on rotavirus …

Background Oral rotavirus vaccines have lower effectiveness in high child mortality settings.
We evaluated the impact of additional dose (s) schedules of rotavirus vaccine on vaccine …

Anemia is a significant public health problem among children worldwide. The etiology of
anemia is multifactorial but iron deficiency (ID) is the most common cause of anemia in low …

Background: Altering rotavirus vaccine schedules may improve vaccine performance in low-
and middle-income countries. We analyzed data from clinical trials of the monovalent (RV1) …

Vaccinations have had tremendous success in the 20th century. However, in the 21st
century, we are facing complex immunological issues in relation to controlling underlying …

Oral rotavirus vaccine efficacy is lower in low-and middle-income countries (LMICs) than in
high-income countries. The degree to which antibiotic use impacts rotavirus vaccine …