Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

Hepatocellular carcinoma (HCC), one of the most common cancers worldwide, is often
diagnosed at an advanced stage when most potentially curative therapies such as resection …

Background—Recent studies have shown that stem cell therapy can promote tissue
regeneration; however, monitoring stem cells in vivo remains problematic owing to …

Suicide gene therapy is based on the introduction into tumor cells of a viral or a bacterial
gene, which allows the conversion of a non-toxic compound into a lethal drug. Although …

Positron emission tomography (PET) allows noninvasive, quantitative studies of various
biologic processes in the tumor tissue. By using PET, investigators can study the …

This review examines the vast catalytic and therapeutic potential offered by type I (ie oxygen-
insensitive) nitroreductase enzymes in partnership with nitroaromatic prodrugs, with …

Molecular imaging includes proteomic, metabolic, cellular biologic process, and genetic
imaging. In a narrow sense, molecular imaging means genetic imaging and can be called …

Current cancer treatments may create profound iatrogenic outcomes. The adverse effects of
these treatments still remain, as the serious problems that practicing physicians have to …

Background—Embryonic stem (ES) cells are distinguished by their capacity for self-renewal
and pluripotency. Here we characterize the differentiation of ES cell–derived endothelial …

Adult stem cells are promising cellular vehicles for therapy of malignant gliomas as they
have the ability to migrate into these tumors and even track infiltrating tumor cells. However …