Pharmaceuticals of emerging concern in aquatic systems: chemistry, occurrence, effects, and removal methods
In the last few decades, pharmaceuticals, credited with saving millions of lives, have
emerged as a new class of environmental contaminant. These compounds can have both …
emerged as a new class of environmental contaminant. These compounds can have both …
Natural products as platforms to overcome antibiotic resistance
SE Rossiter, MH Fletcher, WM Wuest - Chemical reviews, 2017 - ACS Publications
Natural products have served as powerful therapeutics against pathogenic bacteria since
the golden age of antibiotics of the mid-20th century. However, the increasing frequency of …
the golden age of antibiotics of the mid-20th century. However, the increasing frequency of …
Assessment of WHO antibiotic consumption and access targets in 76 countries, 2000–15: an analysis of pharmaceutical sales data
Summary Background The WHO Access, Watch, and Reserve (AWaRe) antibiotic
classification framework aims to balance appropriate access to antibiotics and stewardship …
classification framework aims to balance appropriate access to antibiotics and stewardship …
Global trend of antimicrobial resistance in common bacterial pathogens in response to antibiotic consumption
The emergence of antimicrobial resistance (AMR) is a growing public health threat
worldwide and antibiotic consumption is being increasingly recognized as the main …
worldwide and antibiotic consumption is being increasingly recognized as the main …
Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data
Background Antibiotic drug consumption is a major driver of antibiotic resistance. Variations
in antibiotic resistance across countries are attributable, in part, to different volumes and …
in antibiotic resistance across countries are attributable, in part, to different volumes and …
Pharmaceutical industry wastewater: review of the technologies for water treatment and reuse
C Gadipelly, A Pérez-González, GD Yadav… - Industrial & …, 2014 - ACS Publications
Pharmaceutical compounds are typically produced in batch processes leading to the
presence of a wide variety of products in wastewaters which are generated in different …
presence of a wide variety of products in wastewaters which are generated in different …
Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment—a review
P Verlicchi, M Al Aukidy, E Zambello - Science of the total environment, 2012 - Elsevier
This review focuses on 118 pharmaceuticals, belonging to seventeen different therapeutic
classes, detected in raw urban wastewater and effluent from an activated sludge system, a …
classes, detected in raw urban wastewater and effluent from an activated sludge system, a …
Antibiotic prescribing for adults in ambulatory care in the USA, 2007–09
DJ Shapiro, LA Hicks, AT Pavia… - Journal of Antimicrobial …, 2014 - academic.oup.com
Objectives To determine patterns of ambulatory antibiotic prescribing in US adults, including
the use of broad-spectrum versus narrow-spectrum agents, to provide a description of the …
the use of broad-spectrum versus narrow-spectrum agents, to provide a description of the …
The genetic basis of the fitness costs of antimicrobial resistance: a meta‐analysis approach
T Vogwill, RC MacLean - Evolutionary applications, 2015 - Wiley Online Library
The evolution of antibiotic resistance carries a fitness cost, expressed in terms of reduced
competitive ability in the absence of antibiotics. This cost plays a key role in the dynamics of …
competitive ability in the absence of antibiotics. This cost plays a key role in the dynamics of …
Fluoroquinolones (FQs) in the environment: a review on their abundance, sorption and toxicity in soil
The use of fluoroquinolones (FQs) antibiotics as therapeutic agents and growth promoters is
increasing worldwide; however their extensive uses are also resulting in antibiotic …
increasing worldwide; however their extensive uses are also resulting in antibiotic …