Global epidemiology and outcomes of acute kidney injury

EAJ Hoste, JA Kellum, NM Selby, A Zarbock… - Nature Reviews …, 2018 - nature.com
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …

Paradigms of acute kidney injury in the intensive care setting

JA Kellum, JR Prowle - Nature Reviews Nephrology, 2018 - nature.com
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …

Classifying AKI by urine output versus serum creatinine level

JA Kellum, FE Sileanu, R Murugan… - Journal of the …, 2015 - journals.lww.com
Severity of AKI is determined by the magnitude of increase in serum creatinine level or
decrease in urine output. However, patients manifesting both oliguria and azotemia and …

Vancomycin plus piperacillin-tazobactam and acute kidney injury in adults: a systematic review and meta-analysis

MK Luther, TT Timbrook, AR Caffrey, D Dosa… - Critical care …, 2018 - journals.lww.com
Objectives: The objective of this systematic review and meta-analysis was to assess acute
kidney injury with combination therapy of vancomycin plus piperacillin-tazobactam, in …

Targeting acute kidney injury in COVID-19

JA Kellum, JWO van Till… - Nephrology Dialysis …, 2020 - academic.oup.com
Abstract As of 15 August 2020, Coronavirus disease 2019 (COVID-19) has been reported
in> 21 million people world-wide and is responsible for more than 750,000 deaths. The …

A risk prediction score for acute kidney injury in the intensive care unit

R Malhotra, KB Kashani, E Macedo… - Nephrology Dialysis …, 2017 - academic.oup.com
Background. Acute kidney injury (AKI) is common in critically ill patients and is associated
with high morbidity and mortality. Early identification of high-risk patients provides an …

The Epimed Monitor ICU Database®: a cloud-based national registry for adult intensive care unit patients in Brazil

FG Zampieri, M Soares, LP Borges… - Revista Brasileira de …, 2017 - SciELO Brasil
Objective: To describe the Epimed Monitor Database®, a Brazilian intensive care unit quality
improvement database. Methods: We described the Epimed Monitor® Database, including …

Fluid overload associates with major adverse kidney events in critically ill patients with acute kidney injury requiring continuous renal replacement therapy

CW Woodward, J Lambert, V Ortiz-Soriano… - Critical care …, 2019 - journals.lww.com
Objectives: We examined the association between fluid overload and major adverse kidney
events in critically ill patients requiring continuous renal replacement therapy for acute …

Obesity, acute kidney injury, and mortality in critical illness

J Danziger, KP Chen, J Lee, M Feng… - Critical care …, 2016 - journals.lww.com
Objectives: Although obesity is associated with risk for chronic kidney disease and improved
survival, less is known about the associations of obesity with risk of acute kidney injury and …

Female sex reduces the risk of hospital-associated acute kidney injury: a meta-analysis

J Neugarten, L Golestaneh - BMC nephrology, 2018 - Springer
Background Female sex has been included as a risk factor in models developed to predict
the development of AKI. In addition, the commentary to the Kidney Disease Improving Global …