Anti-angiogenic therapy: current challenges and future perspectives

F Lopes-Coelho, F Martins, SA Pereira… - International journal of …, 2021 - mdpi.com
Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

Müller cells in the healthy and diseased retina

A Bringmann, T Pannicke, J Grosche, M Francke… - Progress in retinal and …, 2006 - Elsevier
Müller glial cells span the entire thickness of the tissue, and ensheath all retinal neurons, in
vertebrate retinae of all species. This morphological relationship is reflected by a multitude …

Blood–retinal barrier in hypoxic ischaemic conditions: basic concepts, clinical features and management

C Kaur, WS Foulds, EA Ling - Progress in retinal and eye research, 2008 - Elsevier
The blood–retinal barrier (BRB) plays an important role in the homeostatic regulation of the
microenvironment in the retina. It consists of inner and outer components, the inner BRB …

Inflammation and metabolic dysfunction: links to cardiovascular diseases

A Taube, R Schlich, H Sell… - American journal of …, 2012 - journals.physiology.org
Abdominal obesity is a major risk factor for cardiovascular disease, and recent studies
highlight a key role of adipose tissue dysfunction, inflammation, and aberrant adipokine …

Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy

R Simo, E Carrasco, M Garcia-Ramirez… - Current diabetes …, 2006 - ingentaconnect.com
Diabetic retinopathy continues to be the leading cause of legal blindness among working-
age individuals. The earliest histological features of diabetic retinopathy include neuroretinal …

Subthreshold diode micropulse laser photocoagulation (SDM) as invisible retinal phototherapy for diabetic macular edema: a review

JK Luttrull, G Dorin - Current Diabetes Reviews, 2012 - ingentaconnect.com
Purpose: To present the state-of-the-art of subthreshold diode laser micropulse
photocoagulation (SDM) as invisible retinal phototherapy for diabetic macular edema …

Müller cells as players in retinal degeneration and edema

A Reichenbach, A Wurm, T Pannicke, I Iandiev… - Graefe's Archive for …, 2007 - Springer
Background Under normal conditions, Müller cells support neuronal activity and the integrity
of the blood-retinal barrier, whereas gliotic alterations of Müller cells under pathological …

Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration

IA Bhutto, DS McLeod, T Hasegawa, SY Kim… - Experimental eye …, 2006 - Elsevier
The purpose of this study was to examine the localization and relative levels of vascular
endothelial growth factor (VEGF; an angiogenic factor) and pigment epithelium-derived …

Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor

L Notari, V Baladron, JD Aroca-Aguilar, N Balko… - Journal of biological …, 2006 - ASBMB
Pigment epithelium-derived factor (PEDF) is an extracellular multifunctional protein
belonging to the serpin superfamily with demonstrable neurotrophic, gliastatic …

Influence of photodynamic therapy on expression of vascular endothelial growth factor (VEGF), VEGF receptor 3, and pigment epithelium–derived factor

U Schmidt-Erfurth… - … & visual science, 2003 - iovs.arvojournals.org
purpose. To evaluate the impact of photodynamic therapy (PDT) on expression and
distribution of vascular endothelial growth factor (VEGF), VEGF receptor (VEGFR)-3, and …