Oocyte activation deficiency and assisted oocyte activation: mechanisms, obstacles and prospects for clinical application

J Kashir, D Ganesh, C Jones… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Oocyte activation deficiency (OAD) is attributed to the majority of cases
underlying failure of ICSI cycles, the standard treatment for male factor infertility. Oocyte …

The therapeutic and diagnostic potential of phospholipase C zeta, oocyte activation, and calcium in treating human infertility

HMR Abdulsamad, ZF Murtaza, HM AlMuhairi… - Pharmaceuticals, 2023 - mdpi.com
Oocyte activation, a fundamental event during mammalian fertilisation, is initiated by
concerted intracellular patterns of calcium (Ca2+) release, termed Ca2+ oscillations …

Effects of kojic acid on boar sperm quality and anti-bacterial activity during liquid preservation at 17 C

W Shaoyong, Q Li, Z Ren, J Xiao, Z Diao, G Yang… - Theriogenology, 2019 - Elsevier
Bacteriospermia is a documented risk to sperm quality when boar semen is stored at 17° C.
The objective of this study was to evaluate the effects of kojic acid (KA) on sperm quality and …

The domestic pig as a model for the study of mitochondrial inheritance

D Zuidema, P Sutovsky - Cell and tissue research, 2020 - Springer
Maternal mitochondrial inheritance is a fundamental paradigm within reproductive biology,
yet the molecular mechanisms which underlie this process remain poorly understood. The …

Effect of chemical activators after intracytoplasmic sperm injection (ICSI) on embryo development in alpacas

DK Bellido-Quispe, FRM Lengua, MC Huamani… - Animal reproduction …, 2024 - Elsevier
Low motility and low sperm concentration are characteristics of alpaca semen. Thus, the
intracytoplasmic sperm injection (ICSI) technique represents an alternative to improve the …

Design of novel oocyte activation methods: The role of zinc

K Uh, A Hay, P Chen, E Reese, K Lee - Biology of Reproduction, 2022 - academic.oup.com
Oocyte activation occurs at the time of fertilization and is a series of cellular events initiated
by intracellular Ca2+ increases. Consequently, oocytes are alleviated from their arrested …

Mobile zinc as a modulator of sensory perception

JM Goldberg, SJ Lippard - FEBS letters, 2023 - Wiley Online Library
Mobile zinc is an abundant transition metal ion in the central nervous system, with pools of
divalent zinc accumulating in regions of the brain engaged in sensory perception and …

The signal that stimulates mammalian embryo development

Z Machaty - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Embryo development is stimulated by calcium (Ca2+) signals that are generated in the egg
cytoplasm by the fertilizing sperm. Eggs are formed via oogenesis. They go through a cell …

ZnSO4 Protects against premature ovarian failure through PI3K/AKT/GSK3β signaling pathway

Z Dong, L Zhang, W Wang, F Jiang, H Ai - Theriogenology, 2023 - Elsevier
Zinc (Zn) is an essential trace element with anti-inflammatory and antioxidant effects and
plays a crucial role in the female reproductive system. We aimed to investigate the protective …

Chemical activation of mammalian oocytes and its application in camelid reproductive biotechnologies: a review

DK Bellido-Quispe, IML Arcce… - Animal Reproduction …, 2024 - Elsevier
Mammalian oocyte activation is a critical process occurring post-gamete fusion, marked by a
sequence of cellular events initiated by an upsurge in intracellular Ca 2+. This surge in …