Noncoding RNAs in age-related cardiovascular diseases

A Jusic, PB Thomas, SB Wettinger, S Dogan… - Ageing Research …, 2022 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …

Targeting the redox system for cardiovascular regeneration in aging

MS Allemann, P Lee, JH Beer, SS Saeedi Saravi - Aging Cell, 2023 - Wiley Online Library
Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …

Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology

SB Nukala, J Jousma, Y Cho, WH Lee, SG Ong - Cell & Bioscience, 2022 - Springer
Cancer is one of the leading causes of morbidity and mortality worldwide. Significant
improvements in the modern era of anticancer therapeutic strategies have increased the …

Preconditioning of umbilical cord‐derived mesenchymal stem cells by rapamycin increases cell migration and ameliorates liver ischaemia/reperfusion injury in mice …

J Zheng, H Li, L He, Y Huang, J Cai, L Chen… - Cell …, 2019 - Wiley Online Library
Objectives Transfusion of umbilical cord‐derived mesenchymal stem cells (UC‐MSCs) is a
novel strategy for treatment of various liver diseases. However, the therapeutic effect of UC …

miR-34a and miR-200c have an additive tumor-suppressive effect on breast cancer cells and patient prognosis

B Mansoori, N Silvestris, A Mohammadi, V Khaze… - Genes, 2021 - mdpi.com
Breast cancer is the most common women's malignancy in the world and, for subgroups of
patients, treatment outcomes remain poor. Thus, more effective therapeutic strategies are …

MiR‐590‐3p regulates proliferation, migration and collagen synthesis of cardiac fibroblast by targeting ZEB1

X Yuan, J Pan, L Wen, B Gong, J Li… - Journal of cellular …, 2020 - Wiley Online Library
Previous studies have implicated the attractive and promising role of miR‐590‐3p to restore
the cardiac function following myocardial infarction (MI). However, the molecular …

MicroRNAs in cancer treatment-induced cardiotoxicity

L Pellegrini, S Sileno, M D'Agostino, E Foglio… - Cancers, 2020 - mdpi.com
Cancer treatment has made significant progress in the cure of different types of tumors.
Nevertheless, its clinical use is limited by unwanted cardiotoxicity. Aside from the …

Developing Nanoceria‐Based pH‐Dependent Cancer‐Directed Drug Delivery System for Retinoblastoma

R Gao, RN Mitra, M Zheng, K Wang… - Advanced functional …, 2018 - Wiley Online Library
Abstract Development of a single combinatorial nanoplatform technology to target cancer
cells has been an unprecedented reality in boosting synergistic antitumor activities and in …

The oxidative stress‐induced miR‐200c is upregulated in psoriasis and correlates with disease severity and determinants of cardiovascular risk

A Magenta, M D'agostino, S Sileno… - Oxidative medicine …, 2019 - Wiley Online Library
Psoriasis is a chronic inflammatory skin disease associated with reactive oxygen species
(ROS) increase and a higher risk of cardiovascular (CV) events. We previously showed that …

Non‐coding RNAs and their potential exploitation in cancer therapy‐related cardiotoxicity

R Bernasconi, GM Kuster - British Journal of Pharmacology, 2025 - Wiley Online Library
Life expectancy in cancer patients has been extended in recent years, thanks to major
breakthroughs in therapeutic developments. However, this also unmasked an increased …