Mitochondria are key cellular organelles that play crucial roles in the energy production and
regulation of cellular metabolism. Accumulating evidence suggests that mitochondrial …

Current antithrombotic therapies used in clinical settings target either the coagulation
pathways or platelet activation receptors (P2Y12 or GPIIb/IIIa), as well as the …

Platelet thrombus formation includes several integrated processes involving aggregation,
secretion of granules, release of arachidonic acid and clot retraction, but it is not clear which …

Platelet activation plays a key role in cardiovascular diseases. The generation of
mitochondrial reactive oxygen species (ROS) has been described as a critical step required …

Platelets are cellular elements that are physiologically involved in hemostasis, inflammation,
thrombotic events, and various human diseases. There is a link between the activation of …

Mitochondria are key regulators of cellular energy and redox metabolism, also playing a
central role in cell signaling and death pathways. A number of processes occur within …

Platelets are anucleated cell elements produced by fragmentation of the cytoplasm of
megakaryocytes and have a unique metabolic phenotype compared with circulating …

Background: Alzheimer's disease (AD) is characterized by an accumulation of amyloid β
(Aβ) peptides in the brain and mitochondrial dysfunction. Platelet activation is enhanced in …

Introduction Platelet mitochondrial respiratory chain enzymes (that produce energy) are
variably inhibited during human sepsis. Whether these changes occur even during other …

Phenylpyrazoles are relatively new insecticides designed to manage problematic insect
resistance and public health hazards encountered with older pesticide families. In vitro …