Allogeneic blood or bone-marrow transplantation (alloBMT) is a potentially curative
treatment for a variety of haematological malignancies and nonmalignant diseases …

Haploidentical donors are now increasingly considered for transplantation in the absence of
HLA-matched donors or when an urgent transplant is needed. Donor-specific anti-HLA …

There is considerable interest in therapeutic transfer of regulatory T cells (Tregs) for
controlling aberrant immune responses. Initial clinical trials have shown the safety of Tregs …

Abstract FOXP3+ regulatory T (Treg) cells are critical in maintaining immune tolerance and
homeostasis of the immune system. The molecular mechanisms underlying the stability …

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by the expansion
of immature myeloid cells in the bone marrow (BM) and peripheral blood (PB) resulting in …

The major cause of death after allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
for acute myeloid leukemia (AML) is disease relapse. We investigated the expression of …

Outcomes after unmanipulated haploidentical stem cell transplantation (Haplo) and after
unrelated cord blood transplantation (UCBT) are encouraging and have become alternative …

Relapse of the original disease is a major cause of death after allogeneic hematopoietic cell
transplantation for acute leukemias. There is growing evidence that relapses may be …

Relapse after autologous or allogeneic hematopoietic stem cell transplantation has become
the most frequent cause of treatment failure. The third International Workshop on Biology …

Regulatory T cells (Tregs) represent a cell type that promotes immune tolerance to
autologous components and maintains immune system homeostasis. The abnormal function …