MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase)
pathway is an important link in the transition from extracellular signals to intracellular …

There is a need for new antifungal agents, mainly due to increased incidence of invasive
fungal infections (IFI), high frequency of associated morbidity and mortality and limitations of …

S-acylation, also known as S-palmitoylation or palmitoylation, is a reversible post-
translational lipid modification in which long chain fatty acid, usually the 16-carbon …

Aspergillus flavus (A. flavus) is a ubiquitous and opportunistic fungal pathogen that causes
invasive and non-invasive aspergillosis in humans and animals. This fungus is also capable …

The genus Aspergillus includes fungal species that cause major health issues of significant
economic importance. These microorganisms are also the culprit for production of …

Fungi inhabit extraordinarily diverse ecological niches, including the human body. Invasive
fungal infections have a devastating impact on human health worldwide, killing∼ 1.5 million …

Ras GTPases belong to one of the small G proteins, which regulate morphology and growth
of filamentous fungi. However, whether Ras GTPases are involved in the biological process …

Epigenetic and posttranslational modifications have been proved to participate in multiple
cellular processes and suggested to be an important regulatory mechanism on transcription …

Post-translational prenylation mechanisms, including farnesylation and geranylgeranylation,
mediate both subcellular localization and protein-protein interaction in eukaryotes. The …

Backgound Fusarium graminearum (FG) is one of the major cereal infecting pathogens
causing high economic losses worldwide and resulting in adverse effects on human and …