Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …
[HTML][HTML] Animal models of anxiety disorders and stress
Anxiety and stress-related disorders are severe psychiatric conditions that affect
performance in daily tasks and represent a high cost to public health. The initial observation …
performance in daily tasks and represent a high cost to public health. The initial observation …
Current status of animal models of posttraumatic stress disorder: behavioral and biological phenotypes, and future challenges in improving translation
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …
Microglial cell hyper-ramification and neuronal dendritic spine loss in the hippocampus and medial prefrontal cortex in a mouse model of PTSD
Few animal models exist that successfully reproduce several core associative and non-
associative behaviours relevant to post-traumatic stress disorder (PTSD), such as long …
associative behaviours relevant to post-traumatic stress disorder (PTSD), such as long …
Biomarkers in posttraumatic stress disorder: overview and implications for future research
PTSD can develop in the aftermath of traumatic incidents like combat, sexual abuse, or life
threatening accidents. Unfortunately, there are still no biomarkers for this debilitating anxiety …
threatening accidents. Unfortunately, there are still no biomarkers for this debilitating anxiety …
Identification and characterization of HPA-axis reactivity endophenotypes in a cohort of female PTSD patients
M Zaba, T Kirmeier, IA Ionescu, B Wollweber… - …, 2015 - Elsevier
Analysis of the function of the hypothalamic–pituitary–adrenal (HPA)-axis in patients
suffering from posttraumatic stress disorder (PTSD) has hitherto produced inconsistent …
suffering from posttraumatic stress disorder (PTSD) has hitherto produced inconsistent …
Modelling posttraumatic stress disorders in animals
Animal models of posttraumatic stress disorder are useful tools to reveal the neurobiological
basis of the vulnerability to traumatic events, and to develop new treatment strategies, as …
basis of the vulnerability to traumatic events, and to develop new treatment strategies, as …
Regulating critical period plasticity: insight from the visual system to fear circuitry for therapeutic interventions
EM Nabel, H Morishita - Frontiers in psychiatry, 2013 - frontiersin.org
Early temporary windows of heightened brain plasticity called critical periods
developmentally sculpt neural circuits and contribute to adult behavior. Regulatory …
developmentally sculpt neural circuits and contribute to adult behavior. Regulatory …
The effect of SSRIs on fear learning: a systematic review and meta-analysis
EJ Heesbeen, EY Bijlsma, PM Verdouw… - …, 2023 - Springer
Rationale Selective serotonin reuptake inhibitors (SSRIs) are considered first-line
medication for anxiety-like disorders such as panic disorder, generalized anxiety disorder …
medication for anxiety-like disorders such as panic disorder, generalized anxiety disorder …
Comparison between cannabidiol and sertraline for the modulation of post-traumatic stress disorder-like behaviors and fear memory in mice
X Han, X Song, D Song, G Xie, H Guo, N Wu, J Li - Psychopharmacology, 2022 - Springer
Rationale and objectives Post-traumatic stress disorder (PTSD) is characterized by poor
adaptation to a traumatic experience and disturbances in fear memory regulation, and …
adaptation to a traumatic experience and disturbances in fear memory regulation, and …