Hydrocephalus: historical analysis and considerations for treatment
Hydrocephalus is a serious condition that affects patients of all ages, resulting from a
multitude of causes. While the etiologies of hydrocephalus are numerous, many of the acute …
multitude of causes. While the etiologies of hydrocephalus are numerous, many of the acute …
Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS
The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and
whose composition changes as a function of an animal's physiological state. Ciliated …
whose composition changes as a function of an animal's physiological state. Ciliated …
The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks …
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks …
[HTML][HTML] A cellular and spatial map of the choroid plexus across brain ventricles and ages
The choroid plexus (ChP) in each brain ventricle produces cerebrospinal fluid (CSF) and
forms the blood-CSF barrier. Here, we construct a single-cell and spatial atlas of each ChP …
forms the blood-CSF barrier. Here, we construct a single-cell and spatial atlas of each ChP …
Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus
Post-hemorrhagic hydrocephalus (PHH) refers to a life-threatening accumulation of
cerebrospinal fluid (CSF) that occurs following intraventricular hemorrhage (IVH). An …
cerebrospinal fluid (CSF) that occurs following intraventricular hemorrhage (IVH). An …
The choroid plexus: a missing link in our understanding of brain development and function
NR Saunders, KM Dziegielewska… - Physiological …, 2023 - journals.physiology.org
Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier,
despite a much longer history. This review has two overall aims. The first is to outline long …
despite a much longer history. This review has two overall aims. The first is to outline long …
The choroid plexus and its role in the pathogenesis of neurological infections
D Thompson, CA Brissette, JA Watt - Fluids and Barriers of the CNS, 2022 - Springer
The choroid plexus is situated at an anatomically and functionally important interface within
the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the …
the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the …
Choroid plexus Aquaporins in CSF homeostasis and the Glymphatic system: their relevance for Alzheimer's disease
C Municio, L Carrero, D Antequera, E Carro - International Journal of …, 2023 - mdpi.com
The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …
Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution
Transmission and secretion of signals via the choroid plexus (ChP) brain barrier can
modulate brain states via regulation of cerebrospinal fluid (CSF) composition. Here, we …
modulate brain states via regulation of cerebrospinal fluid (CSF) composition. Here, we …
Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
EK Oernbo, AB Steffensen… - Fluids and Barriers of …, 2022 - Springer
Background Disturbances in the brain fluid balance can lead to life-threatening elevation in
the intracranial pressure (ICP), which represents a vast clinical challenge. Nevertheless, the …
the intracranial pressure (ICP), which represents a vast clinical challenge. Nevertheless, the …