Sex bias in neuroscience and biomedical research

AK Beery, I Zucker - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
Female mammals have long been neglected in biomedical research. The NIH mandated
enrollment of women in human clinical trials in 1993, but no similar initiatives exist to foster …

Gender differences in the regulation of blood pressure

JF Reckelhoff - Hypertension, 2001 - Am Heart Assoc
Men are at greater risk for cardiovascular and renal disease than are age-matched,
premenopausal women. Recent studies using the technique of 24-hour ambulatory blood …

Subgroup analysis in randomised controlled trials: importance, indications, and interpretation

PM Rothwell - The Lancet, 2005 - thelancet.com
Large pragmatic trials provide the most reliable data about the effects of treatments, but
should be designed, analysed, and reported to enable the most effective use of treatments in …

Women's health and women's leadership in academic medicine: hitting the same glass ceiling?

M Carnes, C Morrissey, SE Geller - Journal of women's health, 2008 - liebertpub.com
The term “glass ceiling” refers to women's lack of advancement into leadership positions
despite no visible barriers. The term has been applied to academic medicine for over a …

The impact of gender on the progression of chronic renal disease

SR Silbiger, J Neugarten - American journal of kidney diseases, 1995 - Elsevier
Observations in experimental animals and in humans have shown that the rate of
progression of renal disease is influenced by gender. Deterioration of renal function in …

Hypertension and health-related quality of life: an epidemiological study in Sweden

C Bardage, DGL Isacson - Journal of clinical epidemiology, 2001 - Elsevier
The aim of this study was to describe the relationship between hypertension and health-
related quality of life (HRQL) in a Swedish general population using the 36-item short form …

Gender effects in pharmacokinetics and pharmacodynamics

RZ Harris, LZ Benet, JB Schwartz - Drugs, 1995 - Springer
There are a number of examples of sex differences in drug pharmacokinetics and
pharmacodynamics. Recent advances in the characterisation of specific isozymes involved …

Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats

JF Reckelhoff, H Zhang, JP Granger - Hypertension, 1998 - Am Heart Assoc
Studies were performed in intact male and female, gonadectomized male and female, and
gonadectomized female rats given testosterone for 5 weeks to investigate the role played by …

Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men: a meta-analysis of individual patient data from randomized, controlled trials

F Gueyffier, F Boutitie, JP Boissel, S Pocock… - Annals of internal …, 1997 - acpjournals.org
Background: Trials of drug therapy for hypertension have shown that such therapy has a
clear overall benefit in preventing cardiovascular disease. Although these trials have …

The primary prevention of coronary heart disease in women

JW Rich-Edwards, JAE Manson… - … England Journal of …, 1995 - Mass Medical Soc
Coronary heart disease has long been recognized as the leading cause of death among
middle-aged men, but it is an equally important cause of death and disability among older …