Comprehensive transcriptome analysis of the periodontopathogenic bacterium Porphyromonas gingivalis W83

H Høvik, WH Yu, I Olsen, T Chen - Journal of bacteriology, 2012 - Am Soc Microbiol
High-density tiling microarray and RNA sequencing technologies were used to analyze the
transcriptome of the periodontopathogenic bacterium Porphyromonas gingivalis. The …

The core genome of the anaerobic oral pathogenic bacterium Porphyromonas gingivalis

J Brunner, FRA Wittink, MJ Jonker, M de Jong… - BMC microbiology, 2010 - Springer
Abstract Background The Gram negative anaerobic bacterium Porphyromonas gingivalis
has long been recognized as a causative agent of periodontitis. Periodontitis is a chronic …

Probing Oral Microbial Functionality – Expression of spxB in Plaque Samples

L Zhu, Y Xu, JJ Ferretti, J Kreth - PloS one, 2014 - journals.plos.org
The Human Oral Microbiome Database (HOMD) provides an extensive collection of genome
sequences from oral bacteria. The sequence information is a static snapshot of the microbial …

Analysis of the FnrL regulon in Rhodobacter capsulatus reveals limited regulon overlap with orthologues from Rhodobacter sphaeroides and Escherichia coli

JE Kumka, CE Bauer - BMC genomics, 2015 - Springer
Background FNR homologues constitute an important class of transcription factors that
control a wide range of anaerobic physiological functions in a number of bacterial species …

Identification of PGN_1123 as the gene encoding lipid A deacylase, an enzyme required for Toll-like receptor 4 evasion, in Porphyromonas gingivalis

S Jain, AM Chang, M Singh, JS McLean… - Journal of …, 2019 - Am Soc Microbiol
Removal of one acyl chain from bacterial lipid A by deacylase activity is a mechanism used
by many pathogenic bacteria to evade the host's Toll-like receptor 4 (TLR4)-mediated innate …

A member of the peptidase M48 superfamily of Porphyromonas gingivalis is associated with virulence in vitro and in vivo

S Walters, M Bélanger, PH Rodrigues… - Journal of oral …, 2009 - Taylor & Francis
Background: In vivo-induced antigen technology was previously used to identify 115 genes
induced in Porphyromonas gingivalis W83 during human infection. One of these, PG2197, a …

The importance of being an antagonist as well as persistent

A Progulske-Fox - Journal of Bacteriology, 2019 - Am Soc Microbiol
The current work by Jain et al.(S. Jain, AM Chang, M. Singh, JS McLean, et al., J Bacteriol
201: e00683-18, 2019, https://doi. org/10.1128/jb. 00683-18) reports the cloning of the lipid …

Methods for identifying inhibitors of lipid a deacylase and expression vectors related to same

RP Darveau, J Sumita - US Patent App. 16/888,696, 2021 - Google Patents
In one embodiment, an expression vector for expressing P. gingivalis lipid A deacylase a
novel screen to identify P. gingivalis deacylase inhibitors. P. gingivalis deacylase inhibitors …

[PDF][PDF] virulence in vitro and in vivo

S Walters, M Belanger, PH Rodrigues, J Whitlock… - Citeseer
Background: In vivo-induced antigen technology was previously used to identify 115 genes
induced in Porphyromonas gingivalis W83 during human infection. One of these, PG2197, a …

[PDF][PDF] Genetic background of Porphyromonas gingivalis capsule biosynthesis

J Brunner - 2011 - dare.uva.nl
The Gram negative anaerobic bacterium Porphyromonas gingivalis has long been
recognized as a causative agent of periodontitis. Periodontitis is a chronic infectious disease …