HIF1α expression under normoxia in prostate cancer—which pathways to target?
WKB Ranasinghe, GS Baldwin, D Bolton, A Shulkes… - The Journal of …, 2015 - Elsevier
Purpose HIF1α over expression correlates with poor prognosis in a number of cancers.
Although it is widely accepted that hypoxia induces HIF1α expression up-regulation by a …
Although it is widely accepted that hypoxia induces HIF1α expression up-regulation by a …
Liquiritigenin Inhibits Serum‐induced HIF‐1α and VEGF Expression via the AKT/mTOR‐p70S6K Signalling Pathway in HeLa Cells
SR Xie, Y Wang, CW Liu, K Luo… - Phytotherapy …, 2012 - Wiley Online Library
Liquiritigenin (LQ) is a non‐toxic dietary flavonoid with chemopreventive and anticancer
properties. However, the mechanism of its antiangiogenesis remains unclear. Hypoxia …
properties. However, the mechanism of its antiangiogenesis remains unclear. Hypoxia …
[HTML][HTML] Mouse melanoma cell migration is dependent on production of reactive oxygen species under normoxia condition
YS Im, YK Ryu, EY Moon - Biomolecules & therapeutics, 2012 - ncbi.nlm.nih.gov
Cell migration plays a role in many physiological and pathological processes. Reactive
oxygen species (ROS) produced in mammalian cells influence intracellular signaling …
oxygen species (ROS) produced in mammalian cells influence intracellular signaling …
A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells
Abstract Background Hypoxia-inducible factor-1 (HIF-1) is a master regulator of the
transcriptional response to hypoxia. It is essential for angiogenesis and is associated with …
transcriptional response to hypoxia. It is essential for angiogenesis and is associated with …
Cooperation of actin-sequestering protein, thymosin β-4 and hypoxia inducible factor-1α in tumor cell migration
YK Ryu, YS Im, EY Moon - Oncology reports, 2010 - spandidos-publications.com
Cell migration plays an important role in many physiological and pathological processes,
including tumor metastasis. Tumor cell migration is increased through the sequential …
including tumor metastasis. Tumor cell migration is increased through the sequential …
Genipin inhibits hypoxia-induced accumulation of HIF-1α and VEGF expressions in human cervical carcinoma cells
CE Jin, JH Lee, GJ Kim, TH Lee - Kosin Medical Journal, 2019 - synapse.koreamed.org
Objectives Hypoxia—a characteristic of almost all types of solid tumors—has been
associated with poor outcomes in several human malignancies. Genipin—an active …
associated with poor outcomes in several human malignancies. Genipin—an active …