Recent stem cell technology provides a strong therapeutic potential not only for acute
ischemic stroke but also for chronic progressive neurodegenerative diseases such as …

Ischemic stroke represents one of the most prevalent pathologies in humans and is a
leading cause of death and disability. Anti-thrombolytic therapy with tissue plasminogen …

Biomaterials composed of mammalian extracellular matrix (ECM) promote constructive
tissue remodeling with minimal scar tissue formation in many anatomical sites. However, the …

Transplantation of human neural stem cells (hNSCs) is emerging as a viable treatment for
stroke related brain injury. However, intraparenchymal grafts do not regenerate lost tissue …

Intracerebral hemorrhagic stroke (ICH) causes high mortality and morbidity with very limited
treatment options. Cell-based therapy has emerged as a novel approach to replace …

Stroke causes significant mortality and morbidity. Currently, there are no treatments which
can regenerate brain tissue lost to infarction. Neural progenitor cells (NPCs) are at the …

Cartilage loss is a leading cause of disability among adults and effective therapy remains
elusive. Neonatal chondrocytes (NChons) are an attractive allogeneic cell source for …

Central nervous system (CNS) pathologies, such as stroke and spinal cord injury, remain
debilitating issues due to the inhibitory environment in the CNS. Many research works have …

Recent studies have indicated that bone marrow stromal cells (BMSC) may improve
neurological function when transplanted into an animal model of CNS disorders, including …

Stem cell therapy for ischemic stroke has widely been explored. Results from both
preclinical and clinical studies have immensely supported the judicious use of stem cells as …