[HTML][HTML] Inorganic pyrophosphate as a regulator of hydroxyapatite or calcium pyrophosphate dihydrate mineral deposition by matrix vesicles

C Thouverey, G Bechkoff, S Pikula, R Buchet - Osteoarthritis and cartilage, 2009 - Elsevier
OBJECTIVE: Pathological mineralization is induced by unbalance between pro-and anti-
mineralization factors. In calcifying osteoarthritic joints, articular chondrocytes undergo …

Matrix vesicles originate from apical membrane microvilli of mineralizing osteoblast‐like Saos‐2 cells

C Thouverey, A Strzelecka‐Kiliszek… - Journal of cellular …, 2009 - Wiley Online Library
In bone, mineralization is tightly regulated by osteoblasts and hypertrophic chondrocytes
which release matrix vesicles (MVs) and control extracellular ionic conditions and matrix …

Carbonic anhydrase I (CA1) is involved in the process of bone formation and is susceptible to ankylosing spondylitis

X Chang, Y Zheng, Q Yang, L Wang, J Pan… - Arthritis research & …, 2012 - Springer
Introduction Ankylosing spondylitis (AS) is characterized by abnormal bone formation in the
spine and the sacroiliac joints. In vitro assays demonstrate that carbonic anhydrase I (CA1) …

Dimethyl sulfoxide-induced hydroxyapatite formation: A biological model of matrix vesicle nucleation to screen inhibitors of mineralization

L Li, R Buchet, Y Wu - Analytical biochemistry, 2008 - Elsevier
To elucidate the inhibition mechanisms of hydroxyapatite (HA), a biological model mimicking
the mineralization process was developed. The addition of 4%(v/v) dimethyl sulfoxide …

Active creatine kinase is present in matrix vesicles isolated from femurs of chicken embryo: Implications for bone mineralization

A Sekrecka-Belniak, M Balcerzak, R Buchet… - Biochemical and …, 2010 - Elsevier
Proteomic analysis of matrix vesicles (MVs) isolated from 17-day-old chicken embryo femurs
revealed the presence of creatine kinase. In this report we identified the enzyme functionally …

[PDF][PDF] Functional Roles of ANKH/Ank: insights from CPPDD-associated ANKH Mutations and the ank/ank Mouse

F Tsui, F Las Heras, R Inman… - J Clin Rheumatol …, 2010 - researchgate.net
Calcium pyrophosphate dihydrate crystal deposition disease (CPPD arthropathy) is a
common form of degenerative arthritis afflicting the elderly. Although the relationships …

Origin, characterization and roles of matrix vesicles in physiological and pathological mineralization.

C Thouverey - 2008 - theses.hal.science
Matrix vesicles (MVs) are involved in the initiation of mineralization in tissues undergoing
physiological and pathological calcification. Pyrophosphate (PPi) has a dual effect on …

[引用][C] 碳酸酐酶1 对骨形成作用的研究

郑亚冰, 王林, 常建芳, 王月俭, 韩金祥, 常晓天 - 中国生物工程杂志, 2012