Recombinant adeno-associated virus (AAV) is the leading vector for gene therapy in the
retina. As non-pathogenic, non-integrating, replication deficient vector, the recombinant virus …

Abstract Adeno-associated virus (AAV)-based vectors are promising tools for gene
therapeutic applications, in part because AAVs are nonpathogenic viruses, and vectors …

Abstract Adeno-associated virus (AAV)-derived viral vectors are a promising platform for the
delivery of curative, life-changing therapies to a huge number of patients with monogenic …

Recombinant adeno-associated viral vectors (rAAVs) have been widely used for gene
delivery in animal models, and are currently evaluated for human gene therapy after …

The recombinant adeno-associated virus (rAAV) gene delivery system is entering a crucial
and exciting phase with the promise of more than 20 years of intense research now realized …

Over 100 human adenoviruses (HAdVs) have been isolated and allocated to seven species,
AG. Species F comprises two members-HAdV-F40 and HAdV-F41. As their primary site of …

Parvoviruses elaborate rugged nonenveloped icosahedral capsids of∼ 260 Å in diameter
that comprise just 60 copies of a common core structural polypeptide. While serving as …

Acute parvovirus B19 infection is a risk for pregnant women. After vertical transmission the
infected fetus may develop hydrops fetalis. Since B19 infection occurs mainly during …

The cytopathic effects induced during parvovirus infection have been widely documented.
Parvovirus infection-induced cell death is often directly associated with disease outcomes …

Porcine parvovirus (PPV) is a major cause of reproductive failure in swine. The mechanisms
implicated in the first steps of infection that lead to the delivery of the PPV genome to the …