Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

DB Kell, N Swainston, P Pir, SG Oliver - Trends in biotechnology, 2015 - cell.com
Because they mainly do not involve chemical changes, membrane transporters have been a
Cinderella subject in the biotechnology of small molecule production, but this is a serious …

Metabolic engineering and fermentation optimization strategies for producing organic acids of the tricarboxylic acid cycle by microbial cell factories

S Zhou, N Ding, R Han, Y Deng - Bioresource Technology, 2023 - Elsevier
The organic acids of the tricarboxylic acid (TCA) pathway are important platform compounds
and are widely used in many areas. The high-productivity strains and high-efficient and low …

Designing a periplasmic photosynthetic biohybrid system for succinate and electric energy production

G Liang, X Xu, X Chen, J Wu, W Song, W Wei… - Chemical Engineering …, 2023 - Elsevier
The emergence of photosynthetic biohybrid systems provides an environmentally friendly
and sustainable approach to produce fuels and chemicals in microbial cell factories …

[图书][B] Fermentation microbiology and biotechnology

EMT El-Mansi, J Nielsen, D Mousdale, RP Carlson - 2018 - books.google.com
Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad
array of metabolic pathways employed for the production of primary and secondary …

Metabolic evolution of two reducing equivalent-conserving pathways for high-yield succinate production in Escherichia coli

X Zhu, Z Tan, H Xu, J Chen, J Tang, X Zhang - Metabolic Engineering, 2014 - Elsevier
Reducing equivalents are an important cofactor for efficient synthesis of target products.
During metabolic evolution to improve succinate production in Escherichia coli strains, two …

Promoter Screening from Bacillus subtilis in Various Conditions Hunting for Synthetic Biology and Industrial Applications

Y Song, JM Nikoloff, G Fu, J Chen, Q Li, N Xie… - PLoS …, 2016 - journals.plos.org
The use of Bacillus subtilis in synthetic biology and metabolic engineering is highly
desirable to take advantage of the unique metabolic pathways present in this organism. To …

Engineering energetically efficient transport of dicarboxylic acids in yeast Saccharomyces cerevisiae

B Darbani, V Stovicek… - Proceedings of the …, 2019 - National Acad Sciences
Biobased C4-dicarboxylic acids are attractive sustainable precursors for polymers and other
materials. Commercial scale production of these acids at high titers requires efficient …

Transporter engineering for microbial manufacturing

Y Zhu, C Zhou, Y Wang, C Li - Biotechnology Journal, 2020 - Wiley Online Library
Microbes play an important role in biotransformation and biosynthesis of biofuels, natural
products, and polymers. Therefore, microbial manufacturing has been widely used in …

Integrating systems and synthetic biology to understand and engineer microbiomes

PA Leggieri, Y Liu, M Hayes, B Connors… - Annual Review of …, 2021 - annualreviews.org
Microbiomes are complex and ubiquitous networks of microorganisms whose seemingly
limitless chemical transformations could be harnessed to benefit agriculture, medicine, and …

Metabolic engineering of Escherichia coli W3110 to produce L‐malate

X Dong, X Chen, Y Qian, Y Wang… - Biotechnology and …, 2017 - Wiley Online Library
ABSTRACT A four‐carbon dicarboxylic acid L‐malate has recently attracted attention due to
its potential applications in the fields of medicine and agriculture. In this study, Escherichia …