The availability of host and dietary carbohydrates in the gastrointestinal (GI) tract plays a key
role in shaping the structure-function of the microbiota. In particular, some gut bacteria have …

Glycoconjugates constitute a major class of biomolecules which include glycoproteins,
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …

[Frontiers in Bioscience 6, d1321-1357, October 1, 2001] 1321 MUCINS IN THE
GASTROINTESTINAL TRACT IN HEALTH AND DISEASE Anthony Page 1 [Frontiers in …

We studied immunohistochemical expression of MUC1, MUC2, and MUC5AC in 194
carcinomas of different primary sites to determine whether differential expression patterns …

The human stomach is a formidable barrier to orally ingested microorganisms and was long
thought to be sterile. The discovery of Helicobacter pylori, a carcinogenic bacterial pathogen …

Intestinal metaplasia (IM) is part of a stepwise sequence of alterations of the gastric mucosa,
leading ultimately to gastric cancer, and is strongly associated with chronic Helicobacter …

Purpose: Mucin expression is a common feature of most adenocarcinomas and features
prominently in current attempts to improve diagnosis and therapy for pancreatic cancer and …

Glycosylation is a common post-translational modification process of proteins. Mucin-type O-
glycosylation is an O-glycosylation that starts from protein serine/threonine residues …

BACKGROUND Crohn's disease (CD) is a chronic relapsing inflammatory bowel disease of
unknown origin. It is characterised by chronic mucosal ulcerations which affect any part of …

Mucins are the most abundant high molecular weight glycoproteins in mucus. Their nature
and glycosylation content dictates the biochemical and biophysical properties of viscoelastic …