Modification‐specific proteomics: strategies for characterization of post‐translational modifications using enrichment techniques
More than 300 different types of protein post‐translational modifications (PTMs) have been
described, many of which are known to have pivotal roles in cellular physiology and …
described, many of which are known to have pivotal roles in cellular physiology and …
High-sensitivity analytical approaches for the structural characterization of glycoproteins
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …
propensity to form varied linkages, substitutions, and branching patterns have fascinated …
Post-translational modifications and mass spectrometry detection
AMN Silva, R Vitorino, MRM Domingues… - Free Radical Biology …, 2013 - Elsevier
In this review, we provide a comprehensive bibliographic overview of the role of mass
spectrometry and the recent technical developments in the detection of post-translational …
spectrometry and the recent technical developments in the detection of post-translational …
HILIC and ERLIC enrichment of glycopeptides derived from breast and brain cancer cells
LG Zacharias, AK Hartmann, E Song… - Journal of proteome …, 2016 - ACS Publications
Aberrant glycosylation has been linked to many different cancer types. The blood–brain
barrier (BBB) is a region of the brain that regulates the entrance of ions, diseases, toxins …
barrier (BBB) is a region of the brain that regulates the entrance of ions, diseases, toxins …
Interaction modes and approaches to glycopeptide and glycoprotein enrichment
Protein glycosylation has received increased attention for its critical role in cell biology and
diseases. Developing new methodologies to discern phenotype-dependent glycosylation …
diseases. Developing new methodologies to discern phenotype-dependent glycosylation …
Glycoprotein enrichment analytical techniques: advantages and disadvantages
Protein glycosylation is one of the most important posttranslational modifications. Numerous
biological functions are related to protein glycosylation. However, analytical challenges …
biological functions are related to protein glycosylation. However, analytical challenges …
[HTML][HTML] Impact of post-translational modifications of crop proteins under abiotic stress
A Hashiguchi, S Komatsu - Proteomes, 2016 - mdpi.com
The efficiency of stress-induced adaptive responses of plants depends on intricate
coordination of multiple signal transduction pathways that act coordinately or, in some …
coordination of multiple signal transduction pathways that act coordinately or, in some …
LC–MS/MS quantitation of esophagus disease blood serum glycoproteins by enrichment with hydrazide chemistry and lectin affinity chromatography
Changes in glycosylation have been shown to have a profound correlation with
development/malignancy in many cancer types. Currently, two major enrichment techniques …
development/malignancy in many cancer types. Currently, two major enrichment techniques …
[HTML][HTML] A universal chemical enrichment method for mapping the yeast N-glycoproteome by mass spectrometry (MS)
Glycosylation is one of the most common and important protein modifications in biological
systems. Many glycoproteins naturally occur at low abundances, which makes …
systems. Many glycoproteins naturally occur at low abundances, which makes …
Proteomic approaches to study structure, functions and toxicity of legume seeds lectins. Perspectives for the assessment of food quality and safety
A Nasi, G Picariello, P Ferranti - Journal of proteomics, 2009 - Elsevier
Lectins are a structurally diverse class of (glyco) proteins which bind mono-and
oligosaccharides with high specificity and in a reversible way. For many years, the unique …
oligosaccharides with high specificity and in a reversible way. For many years, the unique …