Metabolic reprogramming is a hallmark of cancer cells and is used by cancer cells for growth
and survival. Pyruvate kinase muscle isozyme M2 (PKM2) is a limiting glycolytic enzyme that …

Glucose metabolism enzymes and transporters play major role in cancer development and
metastasis. In this study, we discuss glucose metabolism, transporters, receptors, hormones …

Reprogrammed metabolism is a key feature of cancer cells. The pyruvate kinase M2 (PKM2)
isoform, which is commonly upregulated in many human cancers, has been recently shown …

Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as
its key regulator. Curcumin is an extensively-studied anti-cancer compound, however, its …

Cancer cells are characterized by high glycolytic rates to support energy regeneration and
anabolic metabolism, along with the expression of pyruvate kinase isoenzyme M2 (PKM2) …

Tumor cells undergo metabolic rewiring from oxidative phosphorylation towards aerobic
glycolysis to maintain the increased anabolic requirements for cell proliferation. It is widely …

Pyruvate kinase is a key regulator in glycolysis through the conversion of
phosphoenolpyruvate (PEP) into pyruvate. Pyruvate kinase exists in various isoforms that …

El cáncer de cuello uterino se encuentra dentro de las principales causas de muerte en la
mujer, por lo que representa un serio problema de salud. Se ha demostrado, mediante …

Pyruvate kinase isoform M2 (PKM2) converts phosphoenolpyruvate (PEP) to pyruvate and
plays an important role in cancer metabolism. Here, we show that post-translational …

Triple‐negative breast cancer (TNBC) is an aggressive form of breast cancer with limited
treatment modalities and poor prognosis. Metabolic reprogramming in cancer is considered …