An update on the formation in tobacco, toxicity and carcinogenicity of Nʹ-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

LA Peterson, SB Stanfill, SS Hecht - Carcinogenesis, 2024 - academic.oup.com
The tobacco-specific nitrosamines N ʹ-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-
1-(3-pyridyl)-1-butanone (NNK) are considered 'carcinogenic to humans' by the International …

The comprehensive prediction of carcinogenic potency and tumorigenic dose (TD50) for two problematic N-nitrosamines in food: NMAMPA and NMAMBA using …

A Frydrych, K Jurowski - Chemico-Biological Interactions, 2024 - Elsevier
The identification and toxicological assessment of potential carcinogens is of paramount
importance for public health and safety. This study aimed to predict the carcinogenic potency …

[PDF][PDF] Basal cell carcinoma development after combined administration of lisinopril and tamsulosin: links to photocarcinogenesis and nitrosogenesis in the context of …

G Tchernev, I Todorov, L Ivanov, S Kordeva - drugs, 2024 - researchgate.net
The association of nitrosogenesis with skin cancer, and in particular with keratinocytic forms
of skin cancer, is primarily or mainly determined by the activation of carcinogenesis and/or …

[PDF][PDF] Keratinocyte cancers, dysplastic nevi and cutaneous melanoma development after intake of potentially nitrosamine/NDSRIs con-taminated drugs: new data …

S Kordeva, L Ivanov, A Alexandrov, AC Simon… - researchgate.net
The exact pathogenetic mechanism associated with nitrosogenesis and
pharmacooncogenesis/oncopharmacogenesis in keratinocytic cancer and melanoma …

[PDF][PDF] EORGIAN EDICAL EWS

М новости Грузии - Heart failure - researchgate.net
Based on the available clinicopathological correlations, we believe that nitrosamines in
drugs have a similar effect and are part of the key pathway activating skin carcinogenesis …