[HTML][HTML] Peptide-based hydrogels: New materials for biosensing and biomedical applications

R Binaymotlagh, L Chronopoulou, FH Haghighi… - Materials, 2022 - mdpi.com
Peptide-based hydrogels have attracted increasing attention for biological applications and
diagnostic research due to their impressive features including biocompatibility and …

[HTML][HTML] Molecular and metabolic regulation of immunosuppression in metastatic pancreatic ductal adenocarcinoma

SK Gautam, SK Batra, M Jain - Molecular cancer, 2023 - Springer
Immunosuppression is a hallmark of pancreatic ductal adenocarcinoma (PDAC),
contributing to early metastasis and poor patient survival. Compared to the localized tumors …

[HTML][HTML] Engineering neoantigen vaccines to improve cancer personalized immunotherapy

Z Liu, J Lv, Q Dang, L Liu, S Weng, L Wang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Immunotherapy treatments harnessing the immune system herald a new era of personalized
medicine, offering considerable benefits for cancer patients. Over the past years, tumor …

[HTML][HTML] Cancer neoepitopes viewed through negative selection and peripheral tolerance: a new path to cancer vaccines

PK Srivastava - The Journal of Clinical Investigation, 2024 - Am Soc Clin Investig
A proportion of somatic mutations in tumors create neoepitopes that can prime T cell
responses that target the MHC I–neoepitope complexes on tumor cells, mediating tumor …

Immunomodulatory hydrogels for skin wound healing: cellular targets and design strategy

Y He, Y Cen, M Tian - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Skin wounds significantly impact the global health care system and represent a significant
burden on the economy and society due to their complicated dynamic healing processes …

[HTML][HTML] Hydrogel-based therapeutics for pancreatic ductal adenocarcinoma treatment

J Liu, W Wu, Q Zhu, H Zhu - Pharmaceutics, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest malignancies worldwide, is
characteristic of the tumor microenvironments (TME) comprising numerous fibroblasts and …

[HTML][HTML] Nanomaterial Delivery Vehicles for the Development of Neoantigen Tumor Vaccines for Personalized Treatment

X Huang, X Zhu, H Yang, Q Li, L Gai, X Sui, H Lu… - Molecules, 2024 - mdpi.com
Tumor vaccines have been considered a promising therapeutic approach for treating cancer
in recent years. With the development of sequencing technologies, tumor vaccines based on …

Putting the sting back in STING therapy: novel delivery vehicles for improved STING activation

S Khorsandi, K Huntoon, J Lux - Frontiers in Chemical Biology, 2024 - frontiersin.org
Engaging the immune sensing Stimulator of Interferon Genes (STING) pathway has
emerged as a potentially powerful approach to cancer therapy. However, current STING …

The competition of ecological resonances in the quantum metabolic model of cancer: Potential energetic interventions

DW Hollar Jr - Biosystems, 2022 - Elsevier
Cancer (a) represents an atavistic reversion to attempted asexual reproduction;(b)
metastasizes to absorber “soil” tissues based upon temporal, ontogenetic commonalities;(c) …

Myeloid-derived suppressor cells: Emerging players in cancer and beyond

C Jiménez-Cortegana… - International review of …, 2023 - pubmed.ncbi.nlm.nih.gov
Myeloid-derived suppressor cells: Emerging players in cancer and beyond Myeloid-derived
suppressor cells: Emerging players in cancer and beyond Int Rev Cell Mol Biol. 2023:375:xiii-xix …