Mitonuclear Communication in Stem Cell Function

B Peng, Y Wang, H Zhang - Cell Proliferation, 2024 - Wiley Online Library
Mitochondria perform multiple functions within the cell, including the production of ATP and
a great deal of metabolic intermediates, while also contributing to the cellular stress …

Acetate to the rescue: Acetyl-CoA facilitates placental development

J Festa, S Trefely - Cell Stem Cell, 2024 - cell.com
While the placenta regulates nutritional exchange between mother and fetus, Yu et al. reveal
that human placental development is itself nutrient-sensitive. They elucidate entwined …

Maternal bisphenol A (BPA) exposure induces placental dysfunction and health risk in adult female offspring: Insights from a mouse model

H Yue, H Zhu, X Wu, Y Tian, J Zhang, Y Hu, X Ji… - Science of The Total …, 2025 - Elsevier
Bisphenol A (BPA) is an endocrine disruptor that poses multiple risks to human health. In
particular, the potential adverse effects of maternal exposure to BPA on offspring warrant …

Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection

Y Chen, P Wang, S Ma, C Yue, X Liu… - Cell …, 2025 - pubmed.ncbi.nlm.nih.gov
Cells face two challenges after transplantation: recognition and killing by lymphocytes, and
cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to …

Early Prediction of Preeclampsia Based on Transposable Elements signature in cell-free RNA

M Patel, A Saleh, A Dabrowska, F Boulet, AK Sinha… - bioRxiv, 2024 - biorxiv.org
Preeclampsia (PE) is a pregnancy-associated hypertension disorder affecting 5 to 10% of
pregnant women each year worldwide, which leads to adverse maternal and child …

TGF-β3 Promotes Trophoblast Development via ACSS2-Dependent Permissive Lipid Metabolism

F BOFFA, M Moncada, M Lo Sterzo, L Palazzese… - bioRxiv, 2025 - biorxiv.org
Transforming growth factor-beta (TGF-β) supports the in vitro maintenance of embryonic and
trophoblast stem cells. Here, we demonstrated that, in a sheep embryo model, the transition …