Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Objective To study the possible relationship between sperm aneuploidy, sperm DNA
integrity, chromatin packaging, traditional semen parameters, and recurrent pregnancy loss …

Oxidative stress is widely implicated in failed reproductive performance, including infertility,
miscarriage, diabetes-related congenital malformations, and preeclampsia. Maternal obesity …

Several studies have explored the relationship among traditional semen parameters, sperm
DNA fragmentation (SDF), and unexplained recurrent miscarriage (RM); however, the …

It is known that sperm samples from recurrent pregnancy loss (RPL) couples have an
increase in their sperm DNA fragmentation (SDF), but no studies have been performed in …

Having been debated for many years, the presence and role of spermatozoal RNAs is
resolving, and their contribution to development is now appreciated. Data from different …

Evidence is increasing that the integrity of sperm DNA may also be related to implantation
failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in …

Background Several factors have been shown to influence semen parameters, one of which
is sexual abstinence; a clinical criteria included in the semen evaluation to provide …

The aetiopathogenesis of recurrent pregnancy loss (RPL) is heterogeneous. The aim of this
study was to investigate the male factor in Italian couples experiencing RPL following …