Current technology enables the production of highly specific genome modifications with
excellent efficiency and specificity. Key to this capability are targetable DNA cleavage …

Targeted genome editing has become a powerful genetic tool for studying gene function or
for modifying genomes by correcting defective genes or introducing genes. A variety of …

Genome editing using sequence-specific nucleases (SSNs) offers an alternative approach
to conventional genetic engineering and an opportunity to extend the benefits of genetic …

Rare-cleaving endonucleases have emerged as important tools for making targeted
genome modifications. While multiple platforms are now available to generate reagents for …

Mosquitoes are vectors of a number of important human and animal diseases. The
development of novel vector control strategies requires a thorough understanding of …

Self-propagating gene drive technologies have a number of desirable characteristics that
warrant their development for the control of insect pest and vector populations, such as the …

Gene editing with all its own advantages in molecular biology applications has made easy
manipulation of various production hosts with the discovery and implementation of modern …

Buried within the genomes of many microorganisms are genetic elements that encode rare-
cutting homing endonucleases that assist in the mobility of the elements that encode them …

Developmental biology, as all experimental science, is empowered by technological
advances. The availability of genetic tools in some species-designated as model organisms …

Introns are ubiquitous in eukaryotic genomes and have long been considered as 'junk
RNA'but the huge energy expenditure in their transcription, removal, and degradation …