Nanotechnology in vaccine delivery
LJ Peek, CR Middaugh, C Berkland - Advanced drug delivery reviews, 2008 - Elsevier
With very few adjuvants currently being used in marketed human vaccines, a critical need
exists for novel immunopotentiators and delivery vehicles capable of eliciting humoral …
exists for novel immunopotentiators and delivery vehicles capable of eliciting humoral …
Engineering biodegradable polyester particles with specific drug targeting and drug release properties
F Mohamed, CF van der Walle - Journal of pharmaceutical sciences, 2008 - Elsevier
ABSTRACT Poly (lactic acid)(PLA) and poly (lactic‐co‐glycolic acid)(PLGA) microspheres
and nanoparticles remain the focus of intensive research effort directed to the controlled …
and nanoparticles remain the focus of intensive research effort directed to the controlled …
PLGA micro and nanoparticles in delivery of peptides and proteins; problems and approaches
S Mohammadi-Samani, B Taghipour - Pharmaceutical …, 2015 - Taylor & Francis
During the last decades, many of the poorly controlled diseases were treated using newly
developed peptide and proteins. Although the majority of such therapeutic moieties have …
developed peptide and proteins. Although the majority of such therapeutic moieties have …
Concurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesis
SD Patil, F Papadmitrakopoulos, DJ Burgess - Journal of controlled release, 2007 - Elsevier
Localized elution of corticosteroids has been used in suppressing inflammation and fibrosis
associated with implantation and continuous in vivo residence of bio-medical devices …
associated with implantation and continuous in vivo residence of bio-medical devices …
Analysis of initial burst in PLGA microparticles
SD Allison - Expert opinion on drug delivery, 2008 - Taylor & Francis
Background: This review addresses recent advances in the understanding of the
mechanisms that underlie burst release and strategies developed to control burst from poly …
mechanisms that underlie burst release and strategies developed to control burst from poly …
Encapsulation of protein drugs in biodegradable microparticles by co-axial electrospray
A co-axial electrospray process was developed to encapsulate protein-based drugs in
biodegradable polymeric microparticles eliminating the key problem faced by other …
biodegradable polymeric microparticles eliminating the key problem faced by other …
A freeze-dried formulation of bacteriophage encapsulated in biodegradable microspheres
U Puapermpoonsiri, J Spencer… - European Journal of …, 2009 - Elsevier
With the emergence of widespread antibiotic resistance, there has been renewed interest in
the use of bacteriophages. While their potency, safety and specificity have underpinned their …
the use of bacteriophages. While their potency, safety and specificity have underpinned their …
Preparation of uniform-sized exenatide-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency and bio-stability
F Qi, J Wu, Q Fan, F He, G Tian, T Yang, G Ma… - Colloids and surfaces B …, 2013 - Elsevier
Exenatide-loaded poly (d, l-lactic-co-glycolic acid)(PLGA) microspheres hold great potential
as a drug delivery system to treat type 2 diabetes mellitus (T2DM) because they can …
as a drug delivery system to treat type 2 diabetes mellitus (T2DM) because they can …
Bovine Serum Albumin Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery via Dry Powder Inhalation
Purpose Dry powder vaccine delivery via the pulmonary route has gained significant
attention as an alternate route to parenteral delivery. In this study, we investigated bovine …
attention as an alternate route to parenteral delivery. In this study, we investigated bovine …
Biodegradable PLGA85/15 nanoparticles as a delivery vehicle for Chlamydia trachomatis recombinant MOMP-187 peptide
MA Taha, SR Singh, VA Dennis - Nanotechnology, 2012 - iopscience.iop.org
Abstract Development of a Chlamydia trachomatis vaccine has been a formidable task partly
because of an ineffective delivery system. Our laboratory has generated a recombinant …
because of an ineffective delivery system. Our laboratory has generated a recombinant …