Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer

R Stading, G Gastelum, C Chu, W Jiang… - Seminars in cancer …, 2021 - Elsevier
Lung cancer has the second highest incidence and highest mortality compared to all other
cancers. Polycyclic aromatic hydrocarbon (PAH) molecules belong to a class of compounds …

[HTML][HTML] Urinary 8-OHdG as a biomarker for oxidative stress: a systematic literature review and meta-analysis

M Graille, P Wild, JJ Sauvain… - International journal of …, 2020 - mdpi.com
Oxidative stress reflects a disturbance in the balance between the production and
accumulation of reactive oxygen species (ROS). ROS are scavenged by the antioxidant …

Polycyclic aromatic hydrocarbons: from metabolism to lung cancer

B Moorthy, C Chu, DJ Carlin - Toxicological Sciences, 2015 - academic.oup.com
Excessive exposure to polycyclic aromatic hydrocarbons (PAHs) often results in lung cancer,
a disease with the highest cancer mortality in the United States. After entry into the lung …

Influences of polycyclic aromatic hydrocarbon on the epigenome toxicity and its applicability in human health risk assessment

DN Das, N Ravi - Environmental research, 2022 - Elsevier
The existence of polycyclic aromatic hydrocarbons (PAHs) in ambient air is an escalating
concern worldwide because of their ability to cause cancer and induce permanent changes …

Salivary and urinary total antioxidant capacity as biomarkers of oxidative stress in humans

I Peluso, A Raguzzini - Pathology research international, 2016 - Wiley Online Library
Total Antioxidant Capacity (TAC) is a biomarker often used in order to investigate oxidative
stress in many pathological conditions. Saliva and urine can be collected noninvasively and …

1‐Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway

H Miao, XQ Wu, YN Wang, DQ Chen… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose In chronic kidney disease (CKD), patients inevitably reach end‐
stage renal disease and require renal transplant. Evidence suggests that CKD is associated …

Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo (a) pyrene

S Ulasli, S Celik, E Gunay, M Ozdemir… - … Pacific Journal of …, 2013 - avesis.hacettepe.edu.tr
Background: Phytochemical compounds are emerging as a new generation of anticancer
agents with limited toxicity in cancer patients. The purpose of this study was to investigate …

[HTML][HTML] Suppressive effects of rosmarinic acid rich fraction from perilla on oxidative stress, inflammation and metastasis ability in A549 cells exposed to PM via C-Jun …

K Pintha, W Chaiwangyen, S Yodkeeree, M Suttajit… - Biomolecules, 2021 - mdpi.com
Particulate matter from forest fires (PMFF) is an environmental pollutant causing oxidative
stress, inflammation, and cancer cell metastasis due to the presence of polycyclic aromatic …

Pathogenic mechanisms in chronic obstructive pulmonary disease due to biomass smoke exposure

R Silva, M Oyarzún, J Olloquequi - Archivos de Bronconeumología (English …, 2015 - Elsevier
Chronic obstructive pulmonary disease (COPD) mortality and morbidity have increased
significantly worldwide in recent decades. Although cigarette smoke is still considered the …

Biomonitoring of polycyclic aromatic hydrocarbons in the urine of lactating mothers: Urinary levels, association with lifestyle factors, and risk assessment

SF Fernández, O Pardo, A Pastor, V Yusà, M Vento… - Environmental …, 2021 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are pollutants produced during incomplete
combustion of organic matter and several industrial processes. Humans can be exposed to …