The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

Preeclampsia is a major complication of pregnancy manifested as hypertension and often
intrauterine growth restriction, but the underlying pathophysiological mechanisms are …

Preeclampsia is a pregnancy-related disorder characterized by hypertension and could lead
to maternal and fetal morbidity and mortality. Although the causative factors and …

Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that are encoded
by the genomes of most organisms. They regulate gene expression through …

The differences between males and females begin shortly after birth, continue throughout
prenatal development, and eventually extend into childhood and adult life. Male embryos …

Aims Epigenetic regulators, including microRNAs (miRNAs), are implicated in type 2
diabetes, but evidence linking circulating miRNAs in pregnancy and risk of gestational …

During the pregnancy associated syndrome preeclampsia (PE), there is increased release
of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin …

Preeclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality
worldwide. Defects in trophoblast invasion, differentiation of extravillous trophoblasts and …