The immune systems of post-pubescent males and females differ significantly with profound
consequences to health and disease. In many cases, sex-specific differences in the immune …

The common variable immunodeficiency disorders are a mixed group of heterogeneous
conditions linked by lack of immunoglobulin production and primary antibody failure. This …

The demographics, immunologic parameters, medical complications, and mortality statistics
from 473 subjects with common variable immune deficiency followed over 4 decades in New …

Non-infectious complications in common variable immunodeficiency (CVID) have emerged
as a major clinical challenge. Detailed clinical spectrum, organ-specific pathologies and …

A major diagnostic intervention in the consideration of many patients suspected to have
primary immunodeficiency diseases (PIDDs) is the application and interpretation of …

B-cell survival depends on signals induced by B-cell activating factor (BAFF) binding to its
receptor (BAFF-R). In mice, mutations in BAFF or BAFF-R cause B-cell lymphopenia and …

Common variable immunodeficiency is a rare immune deficiency, characterized by low
levels of serum immunoglobulin G, A, and/or M with loss of antibody production. The …

Common variable immunodeficiency (CVID) is a rare immune deficiency characterized by
low levels of serum IgG, IgA, and/or IgM, with a loss of Ab production. The diagnosis is most …

A proportion of people living with common variable immunodeficiency disorders develop
granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a …

A 5-years multicenter prospective study on 201 patients with common variable
immunodeficiencies and 101 patients with X-linked agammaglobulinemia over a cumulative …