An overview of aryl hydrocarbon receptor ligands in the Last two decades (2002–2022): A medicinal chemistry perspective
L Lin, Y Dai, Y Xia - European Journal of Medicinal Chemistry, 2022 - Elsevier
The aryl hydrocarbon receptor (AhR), discovered 46 years ago, is a transcript factor member
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …
The role of the aryl hydrocarbon receptor (AhR) and its ligands in breast cancer
Simple Summary The aryl hydrocarbon receptor (AhR) is expressed in breast cancer cells
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …
Prediction and screening model for products based on fusion regression and xgboost classification
J Wu, L Kong, M Yi, Q Chen, Z Cheng… - Computational …, 2022 - Wiley Online Library
Performance prediction based on candidates and screening based on predicted
performance value are the core of product development. For example, the performance …
performance value are the core of product development. For example, the performance …
Aryl hydrocarbon receptor as an anticancer target: An overview of ten years odyssey
Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor belonging to the
basic helix–loop–helix (bHLH)/per-Arnt-sim (PAS) superfamily, is traditionally known to …
basic helix–loop–helix (bHLH)/per-Arnt-sim (PAS) superfamily, is traditionally known to …
Design, Synthesis, Docking, 2D‐QSAR Modelling, Anticancer and Antioxidant Evaluation of Some New Azo‐Compounds Derivatives and Investigation of Their …
EO Hamed, DA Elsayed, MG Assy… - ChemistrySelect, 2022 - Wiley Online Library
Abstract 2, 2′(2, 4‐dioxopentane‐3, 3‐diyl) bis (diazene‐2, 1‐diyl) dibenzoic acid was
produced in this work, which was derived from the coupling reaction between two moles of …
produced in this work, which was derived from the coupling reaction between two moles of …
[HTML][HTML] QSAR Regression Models for Predicting HMG-CoA Reductase Inhibition
Background/Objectives: HMG-CoA reductase is an enzyme that regulates the initial stage of
cholesterol synthesis, and its inhibitors are widely used in the treatment of cardiovascular …
cholesterol synthesis, and its inhibitors are widely used in the treatment of cardiovascular …
Amino alcohols as potential antibiotic and antifungal leads
Five focused compound libraries (forty-nine compounds), based on prior studies in our
laboratory were synthesized and screened for antibiotic and anti-fungal activity against S …
laboratory were synthesized and screened for antibiotic and anti-fungal activity against S …
Structural effects of sulfonamides on the proliferation dynamics of sulfonamide resistance genes in the sequencing batch reactors and the mechanism
L Wu, M Wang, L Rong, W Wang, L Chen, Q Wu… - Journal of …, 2024 - Elsevier
Antibiotic resistance genes (ARGs) can be easily promoted by antibiotics, however, the
structural effects of antibiotics on the proliferation of ARGs dynamic and the associated …
structural effects of antibiotics on the proliferation of ARGs dynamic and the associated …
QSAR Based Drug Repurposing: A New Paradigm in Breast Cancer Research
R Mohapatra, P Panda, SS Rout - Indian Journal of Pharmaceutical …, 2024 - ijper.org
Breast carcinoma is the world's most prevalent type of cancer. The building of predictive
cytotoxicity breast cancer models assists permanent synthetic activities and give critical …
cytotoxicity breast cancer models assists permanent synthetic activities and give critical …
Deregulation of drug metabolizing enzymes and transporters in cancer via altered aryl hydrocarbon receptor signaling
G Vázquez-Gómez, J Vondráček - Resistance in Hematologic …, 2025 - Elsevier
The aryl hydrocarbon receptor (AhR) is a transcription factor belonging to the basic helix-
loop-helix Per-ARNT-Sim family of transcriptional regulators and a major regulator of …
loop-helix Per-ARNT-Sim family of transcriptional regulators and a major regulator of …