Cytokine-polymorphisms associated with Preeclampsia: A review

C Mora-Palazuelos, M Bermúdez, M Aguilar-Medina… - Medicine, 2022 - journals.lww.com
Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of
pregnancies and is diagnosed principally when hypertension appears in the second-d half …

The role of interleukins in preeclampsia: a comprehensive review

I Bellos, V Karageorgiou, D Kapnias… - American Journal of …, 2018 - Wiley Online Library
Preeclampsia is a multi‐system hypertensive disorder of pregnancy, with significant rates of
maternal and neonatal morbidity. It represents a major cause of preterm birth, as definitive …

Pregnancy, preeclampsia and maternal aging: From epidemiology to functional genomics

EC Miller, A Wilczek, NA Bello, S Tom, R Wapner… - Ageing research …, 2022 - Elsevier
Women live longer than men but experience greater disability and a longer period of illness
as they age. Despite clear sex differences in aging, the impact of pregnancy and its …

Implications of the cGAS-STING pathway in diabetes: Risk factors and therapeutic strategies

S Mohammadi, M Khorasani - International Journal of Biological …, 2024 - Elsevier
Diabetes mellitus is an increasingly prevalent metabolic disorder characterized by chronic
hyperglycemia and impaired insulin action. Although the pathogenesis of diabetes is …

A review of key cytokines based on gene polymorphism in the pathogenesis of pre‐eclampsia

C Guan, F Zhao, Z Yang, Q Tang… - American Journal of …, 2022 - Wiley Online Library
Although a number of theories have been suggested, including roles for oxidative stress, an
abnormal maternal‐fetal interface, and genetic and environmental factors, the etiopathology …

Associations of common IL-4 gene polymorphisms with cancer risk: A meta-analysis

Y Jia, X Xie, X Shi, S Li - Molecular medicine reports, 2017 - spandidos-publications.com
Cancer incidence is dramatically increasing worldwide, therefore improved prediction and
therapeutic methods are needed. Single nucleotide polymorphisms in cytokine genes may …

Interleukin-1β (IL-1β) & IL-4 gene polymorphisms in patients with systemic lupus erythematosus (SLE) & their association with susceptibility to SLE

M Mohammadoo-Khorasani, S Salimi… - Indian Journal of …, 2016 - journals.lww.com
Methods: One hundred and sixty three SLE patients and 180 healthy controls were
genotyped for the IL-4 VNTR (variable number tandem repeat), IL-1β C-511T and IL-1β T …

[HTML][HTML] Detection of IL-1β, VEGF and IL-4 with their novel genetic variations in breast cancer patients

TF Mohammed, FA Qadir - Saudi Journal of Biological Sciences, 2023 - Elsevier
Abstract Interleukin-1β (IL-1β), vascular endothelial growth factor (VEGF), and IL-4 serum
levels and new genetic mutations in breast cancer (BC) patients were assessed in the …

Candidate gene, genome-wide association and bioinformatic studies in pre-eclampsia: a review

S Thakoordeen, J Moodley, T Naicker - Current hypertension reports, 2018 - Springer
Abstract Purpose of Review Regardless of the familial linkage reported in pre-eclampsia
development, understanding the polymorphic genes associated with pre-eclampsia remains …

Increase of circulating inflammatory molecules in preeclampsia, an update

G Guney, MI Taskin, A Tokmak - European Cytokine Network, 2020 - Springer
Special hormonal and immunological changes are required for normal pregnancy
continuation. To escape from rejection by the maternal immune system, pregnancy needs an …