Laryngopharyngeal reflux and voice disorders: a multifactorial model of etiology and pathophysiology
JR Lechien, S Saussez, B Harmegnies, C Finck… - Journal of voice, 2017 - Elsevier
Objective The aim of this paper is to shed light on the pathogenesis and pathophysiological
mechanisms underlying the development of hoarseness related to laryngopharyngeal reflux …
mechanisms underlying the development of hoarseness related to laryngopharyngeal reflux …
Voice disorders: etiology and diagnosis
RHG Martins, HA do Amaral, ELM Tavares, MG Martins… - Journal of voice, 2016 - Elsevier
Objectives Voice disorders affect adults and children and have different causes in different
age groups. The aim of the study is to present the etiology and diagnosis dysphonia in a …
age groups. The aim of the study is to present the etiology and diagnosis dysphonia in a …
Laryngopharyngeal reflux: current concepts and questions
R Gupta, RT Sataloff - Current Opinion in Otolaryngology & Head …, 2009 - journals.lww.com
Laryngopharyngeal reflux remains a controversial diagnosis. Treatment with proton pump
inhibitors persists despite weak evidence supporting or refuting their utility, and well …
inhibitors persists despite weak evidence supporting or refuting their utility, and well …
Pepsin as a causal agent of inflammation during nonacidic reflux
TL Samuels, N Johnston - Otolaryngology--Head and Neck …, 2009 - journals.sagepub.com
Objective: To investigate the contribution of pepsin to inflammation attributed to nonacidic
gastric reflux via analysis of inflammatory cytokine and cytokine receptor gene expression in …
gastric reflux via analysis of inflammatory cytokine and cytokine receptor gene expression in …
A double-chamber rotating bioreactor for the development of tissue-engineered hollow organs: from concept to clinical trial
MA Asnaghi, P Jungebluth, MT Raimondi… - Biomaterials, 2009 - Elsevier
Cell and tissue engineering are now being translated into clinical organ replacement,
offering alternatives to fight morbidity, organ shortages and ethico-social problems …
offering alternatives to fight morbidity, organ shortages and ethico-social problems …
Gastric reflux is an independent risk factor for laryngopharyngeal carcinoma
Background: Gastric reflux can reach into the upper airway, inducing cellular damage in the
epithelial lining. This condition is believed to be a risk factor for development of …
epithelial lining. This condition is believed to be a risk factor for development of …
Impact of laryngopharyngeal reflux on subjective and objective voice assessments: a prospective study
JR Lechien, K Huet, M Khalife… - … -Head & Neck …, 2016 - journals.sagepub.com
Background Laryngopharyngeal reflux is a prevalent, not well-understood disease affecting
a high proportion of patients who seek laryngology consultation. The objective of this …
a high proportion of patients who seek laryngology consultation. The objective of this …
Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux
JR Lechien, F Bobin, F Mouawad, K Zelenik… - European Archives of …, 2019 - Springer
Objective To develop clinical tools assessing the refluxogenic potential of foods and
beverages (F&B) consumed by patients with laryngopharyngeal reflux (LPR). Methods …
beverages (F&B) consumed by patients with laryngopharyngeal reflux (LPR). Methods …
Voice outcomes of laryngopharyngeal reflux treatment: a systematic review of 1483 patients
JR Lechien, C Finck, P Costa de Araujo, K Huet… - European archives of …, 2017 - Springer
The aim of this study is to explore voice quality modifications in laryngopharyngeal reflux
(LPR) disease and to understand better the pathophysiological mechanisms underlying the …
(LPR) disease and to understand better the pathophysiological mechanisms underlying the …
Laryngopharyngeal reflux and inflammatory responses in mucosal barrier dysfunction of the upper aerodigestive tract
D Liu, T Qian, S Sun, JJ Jiang - Journal of Inflammation Research, 2021 - Taylor & Francis
The upper aerodigestive tract (UAT) is the first line of defense against environmental
stresses such as antigens, microbes, inhalants, foods, etc., and mucins, intracellular …
stresses such as antigens, microbes, inhalants, foods, etc., and mucins, intracellular …