New families of carboxyl peptidases: serine-carboxyl peptidases and glutamic peptidases

K Oda - The journal of biochemistry, 2012 - academic.oup.com
Peptidases or proteinases are now classified into seven families based on the nature of the
catalytic residues [MEROPS—the peptidase database (http://merops. sanger. ac. uk/)]. They …

Thermophilic molds: biology and applications

B Singh, MJ Poças-Fonseca, BN Johri… - Critical reviews in …, 2016 - Taylor & Francis
Thermophilic molds thrive in a variety of natural habitats including soils, composts, wood
chip piles, nesting materials of birds and other animals, municipal refuse and others, and …

Global identification of peptidase specificity by multiplex substrate profiling

AJ O'donoghue, AA Eroy-Reveles, GM Knudsen… - Nature …, 2012 - nature.com
We developed a simple and rapid multiplex substrate-profiling method to reveal the
substrate specificity of any endo-or exopeptidase using liquid chromatography–tandem …

[HTML][HTML] Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis

CA Desjardins, MD Champion, JW Holder… - PLoS …, 2011 - journals.plos.org
Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-
threatening human systemic mycosis endemic to Latin America. Infection by …

[HTML][HTML] Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase

AJ O'Donoghue, Y Jin, GM Knudsen, NC Perera… - PloS one, 2013 - journals.plos.org
Neutrophil extracellular traps (NETs) consist of antimicrobial molecules embedded in a web
of extracellular DNA. Formation of NETs is considered to be a defense mechanism utilized …

Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome

AJ O'Donoghue, GM Knudsen… - Proceedings of the …, 2015 - National Acad Sciences
Pseudogymnoascus destructans is the causative agent of white-nose syndrome, a disease
that has caused the deaths of millions of bats in North America. This psychrophilic fungus …

[HTML][HTML] Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy

L del Amo-Maestro, SR Mendes… - Nature …, 2022 - nature.com
The digestion of gluten generates toxic peptides, among which a highly immunogenic
proline-rich 33-mer from wheat α-gliadin, that trigger coeliac disease. Neprosin from the …

[HTML][HTML] Extracellular peptidases of the cereal pathogen Fusarium graminearum

RGT Lowe, O McCorkelle, M Bleackley… - Frontiers in Plant …, 2015 - frontiersin.org
The plant pathogenic fungus Fusarium graminearum (Fgr) creates economic and health
risks in cereals agriculture. Fgr causes head blight (or scab) of wheat and stalk rot of corn …

In vivo gene expression profiling of the entomopathogenic fungus Beauveria bassiana elucidates its infection stratagems in Anopheles mosquito

Y Lai, H Chen, G Wei, G Wang, F Li, S Wang - Science China Life …, 2017 - Springer
The use of entomopathogenic fungi to control mosquitoes is a promising tool for reducing
vector-borne disease transmission. To better understand infection stratagems of insect …

[HTML][HTML] Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival …

SC Clarke, PA Dumesic, CM Homer… - PLoS …, 2016 - journals.plos.org
The opportunistic fungal pathogen Cryptococcus neoformans is a major cause of mortality in
immunocompromised individuals, resulting in more than 600,000 deaths per year. Many …