Snakebite associated thrombotic microangiopathy and recommendations for clinical practice

T Noutsos, BJ Currie, ES Wijewickrama, GK Isbister - Toxins, 2022 - mdpi.com
Snakebite is a significant and under-resourced global public health issue. Snake venoms
cause a variety of potentially fatal clinical toxin syndromes, including venom-induced …

Snakebite associated thrombotic microangiopathy: a systematic review of clinical features, outcomes, and evidence for interventions including plasmapheresis

T Noutsos, BJ Currie, RA Lek… - PLoS neglected tropical …, 2020 - journals.plos.org
Snakebite is a neglected tropical disease with significant morbidity and mortality. Thrombotic
microangiopathy (TMA) is an important but poorly understood complication of snakebite …

Evolutionary interpretations of nicotinic acetylcholine receptor targeting venom effects by a clade of Asian Viperidae snakes

RJ Harris, CN Zdenek, J Debono, D Harrich… - Neurotoxicity …, 2020 - Springer
Ecological variability among closely related species provides an opportunity for evolutionary
comparative studies. Therefore, to investigate the origin and evolution of neurotoxicity in …

Basal but divergent: Clinical implications of differential coagulotoxicity in a clade of Asian vipers

J Debono, MHA Bos, F Coimbra, L Ge, N Frank… - Toxicology in vitro, 2019 - Elsevier
Envenomations by Asian pitvipers can induce multiple clinical complications resulting from
coagulopathic and neuropathic effects. While intense research has been undertaken for …

Kidney injury following envenoming by hump-nosed pit viper (Genus: Hypnale) in Sri Lanka: proven and probable cases

RN Rathnayaka, PEAN Ranathunga… - Transactions of the …, 2019 - academic.oup.com
Background Hump-nosed pit vipers (Hypnale hypnale) are highly venomous snakes found
in Sri Lanka and the Western Ghats region of India. They are the most common cause of …

Thrombotic Microangiopathy, Hemolytic Uremic Syndrome, and Thrombotic Thrombocytopenic Purpura Following Hump-nosed Pit Viper (Genus: Hypnale) …

R Namal Rathnayaka… - Wilderness & …, 2019 - journals.sagepub.com
Thrombotic microangiopathy (TMA), which includes the spectrum of hemolytic uremic
syndrome and thrombotic thrombocytopenic purpura, is an uncommon complication of hump …

Thrombotic microangiopathy due to Viperidae bite: Two case reports

T Dineshkumar, J Dhanapriya… - Indian journal of …, 2017 - journals.lww.com
Snake bite is mainly an occupational hazard and causes serious health problems in rural
India. Acute kidney injury (AKI) occurs in 5-30% cases. Renal pathologic findings include …

Thrombotic microangiopathy following Bothrops jararaca snakebite: case report

F Bucaretchi, MMB Pimenta… - Clinical …, 2019 - Taylor & Francis
Context: Thrombotic microangiopathy (TMA) is an uncommon and severe complication of
snakebites, and is similar, in general, to hemolytic-uremic syndrome (HUS). We describe a …

Severe acute kidney injury following Sri Lankan Hypnale spp. envenoming is associated with thrombotic microangiopathy

ES Wijewickrama, LV Gooneratne… - Clinical …, 2021 - Taylor & Francis
Context Acute kidney injury (AKI) is the most serious clinical manifestation of the Sri Lankan
hump-nosed pit viper (Hypnale spp.) bites. Thrombotic microangiopathy (TMA) is …

Platelet Desialylation Is a Novel Mechanism and Therapeutic Target in Daboia siamensis and Agkistrodon halys Envenomation-Induced Thrombocytopenia

C Zhang, Z Zhang, E Liang, Y Gao, H Li, F Xu, W Chen… - Molecules, 2022 - mdpi.com
Venom-induced thrombocytopenia (VIT) is one of the most important hemotoxic effects of a
snakebite, which is often associated with venom-induced consumptive coagulopathy (VICC) …