Antimicrobial resistance is one of the greatest challenges of the 21st century. Evaluation of
the public health burden of antimicrobial resistance, which is needed to drive policy …

Given the global burden of tuberculosis, shortened treatment regimens with existing or
repurposed drugs are needed to contribute to tuberculosis control. The long duration of …

Purpose This systematic review aims to evaluate the existing evidence associating linezolid
to serotonin toxicity when used as monotherapy or when co-administered with other …

A challenge in tuberculosis treatment regimen design is the necessity to combine three or
more antibiotics. We narrow the prohibitively large search space by breaking down high …

Background Determining the activity of pulmonary tuberculosis on chest radiographs is
difficult. Purpose To develop a deep learning model to identify active pulmonary tuberculosis …

Background Linezolid is recommended for treating drug-resistant TB. Adverse events are a
concern to prescribers but have not been systematically studied at the standard dose, and …

Cocrystals have been extensively used to improve the physicochemical properties and
bioavailability of active pharmaceutical ingredients. Cocrystals of anti-tuberculosis …

Background Two weeks' isolation is widely recommended for people commencing treatment
for pulmonary tuberculosis (TB). The evidence that this corresponds to clearance of …

Tuberculous meningitis (TB meningitis) is the most devastating form of tuberculosis (TB) and
there is a critical need to optimize treatment. Linezolid is approved for multidrug resistant TB …

Genitourinary tuberculosis (GUTB) represents a disease often underestimated by urological
specialists, particularly in settings such as the European one, where the pathology is less …