HIV-associated cryptococcal meningitis

JN Jarvis, TS Harrison - Aids, 2007 - journals.lww.com
While the incidence of cryptococccal meningitis in the developed world has declined with
widespread, early antiretroviral therapy (ART), cryptococcal disease remains a major …

Comparison of the early fungicidal activity of high-dose fluconazole, voriconazole, and flucytosine as second-line drugs given in combination with amphotericin B for …

A Loyse, D Wilson, G Meintjes, JN Jarvis… - Clinical infectious …, 2012 - academic.oup.com
Abstract (See the Editorial Commentary by Bennett, on pages 129–30.) Background. HIV-
associated cryptococcal meningitis is associated with an estimated 600 000 deaths …

Efficacy of voriconazole in Japanese quail (Coturnix japonica) experimentally infected with Aspergillus fumigatus

LA Tell, KV Clemons, Y Kline, L Woods… - Medical …, 2010 - academic.oup.com
Aspergillus fumigatus causes disease in birds. Our objectives were to determine
pharmacokinetic parameters and evaluate efficacy of voriconazole (VCZ) in a novel …

Comparison of amphotericin B deoxycholate in combination with either flucytosine or fluconazole, and voriconazole plus flucytosine for the treatment of HIV …

T Zhao, X Xu, Y Wu, W Zhang, Q Zeng, Y Lu… - BMC Infectious …, 2022 - Springer
Background The most appropriate alternative to induction therapy for HIV-associated
cryptococcal meningitis (CM) remains unclear when standard treatment is unavailable …

Amphotericin B plus fluorocytosine combined with voriconazole for the treatment of non-HIV and non-transplant-associated cryptococcal meningitis: a retrospective …

J Liu, J Liu, X Su, L Yang, Y Wang, A Wang, X Xu, M Li… - BMC neurology, 2022 - Springer
Background Our previous study explored Amphotericin B (AMB) plus 5-flucytosine (5-FC)
combined with fluconazole (FLU) therapy in the induction period, which seemed to be better …

Effects of Double and Triple Combinations of Antifungal Drugs in a Murine Model of Disseminated Infection by Scedosporium prolificans

MM Rodríguez, E Calvo, C Serena… - Antimicrobial agents …, 2009 - Am Soc Microbiol
We have evaluated the efficacies of micafungin, amphotericin B, and voriconazole, alone
and in double and triple combinations, in a murine model of systemic infection by …

Successful salvage therapy of refractory HIV-related cryptococcal meningitis with the combination of liposomal amphotericin B, voriconazole, and recombinant …

MN Gamaletsou, NV Sipsas, DP Kontoyiannis… - … and infectious disease, 2012 - Elsevier
We present 2 cases of HIV-related cryptococcal meningitis, persisting after 3 and 9 months,
respectively, of standard treatment. Both patients were treated successfully with a salvage …

Voriconazole plus flucytosine is not superior to amphotericin B deoxycholate plus flucytosine as an induction regimen for cryptococcal meningitis treatment

H Zhao, Y Lu, S Li, J Qin, M Xu, H Ye, Z Yang, J Rao… - Mycoses, 2024 - Wiley Online Library
Background The efficacy and side effects of voriconazole plus 5‐flucytosine (Vori+ 5‐FC)
versus amphotericin B deoxycholate plus 5‐flucytosine (AmBd+ 5‐FC) as an induction …

Efficacy of voriconazole in vitro and in invertebrate model of cryptococcosis

C de Castro Spadari, FWM da Silva de Bastiani… - Archives of …, 2020 - Springer
Cryptococcosis is a common opportunistic infection in patients with advanced HIV infection
and may also affect immunocompetent patients. The available antifungal agents are few and …

The development of animal infection models and antifungal efficacy assays against clinical isolates of Trichosporon asahii, T. asteroides and T. inkin

M Mariné, VLP Bom, PA de Castro, LK Winkelstroter… - Virulence, 2015 - Taylor & Francis
The present study developed Galleria mellonella and murine infection models for the study
of Trichosporon infections. The utility of the developed animal models was demonstrated …