Tomato and its derived products have a very interesting nutritional value in addition to
prominent antioxidant, anti-inflammatory, and anticancer activities. Tomatoes are generally …

Mitochondria are major sources of reactive oxygen species (ROS) within the cell and are
especially vulnerable to oxidative stress. Oxidative damage to mitochondria results in …

Carotenoids, symmetrical tetraterpenes with a linear C40 hydrocarbon backbone, are
natural pigment molecules produced by plants, algae, and fungi. Carotenoids have …

Atrazine (ATR), an environmental persistent and bioaccumulative herbicide, has been
associated with environmental nephrosis. Lycopene (LYC) exhibits important properties of …

Oxidative stress plays a very critical role in neurodegenerative diseases, such as
Parkinson's disease (PD), which is the second most common neurodegenerative disease …

Zearalenone (ZEA) has an estrogenic effect and often causes reproductive damage. Pigs
are particularly sensitive to it. Lycopene (LYC) is a type of fat-soluble natural carotenoid that …

The present study aimed to investigate the neuroprotective effect of lycopene in a mouse
model of bilateral common carotid artery occlusion (BCCAO) and the role of the Nrf2/HO‑1 …

Oxidative stress, which is characterized by excessive production of reactive oxygen species
(ROS), is a common pathway that results in neuronal injury or death due to various types of …

Autophagy is an evolutionarily conserved process that degrades damaged organelles and
recycles macromolecules to support cell survival. However, in certain disease states …

Background: Oral uptake of lycopene has been shown to be beneficial for preventing
myocardial ischemia-reperfusion (I/R) injury. However, the strong first-pass metabolism of …