Compulsion is a cardinal symptom of drug addiction (severe substance use disorder).
However, compulsion is observed in only a small proportion of individuals who repeatedly …

A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirical effort to address
limitations of traditional mental disorder diagnoses. These include arbitrary boundaries …

Relatively little is known about the neuropathophysiology of binge-eating disorder (BED).
Here, the evidence from neuroimaging, neurocognitive, genetics, and animal studies are …

Previous large-scale studies suggest that internet gaming disorder (IGD) among children
and adolescents has become an important public concern. Minors are known to be …

Trait impulsivity is a multifaceted personality characteristic that contributes to maladaptive
life outcomes. Although a growing body of neuroimaging studies have investigated the …

The ability to stop already-initiated actions is a key cognitive control ability. Recent work on
human action-stopping has been dominated by two controversial debates. First, the …

Major depressive disorder (MDD) and substance use disorders (SUDs) are prevalent,
disabling, and challenging illnesses for which new treatment options are needed …

Punishment involves learning about the relationship between behavior and its adverse
consequences. Punishment is fundamental to reinforcement learning, decision-making and …

BackgroundNumerous studies of resting-state functional imaging and voxel-based
morphometry (VBM) have revealed differences in specific brain regions of patients with …